Results 81 to 90 of about 4,603,460 (290)
Knowledge base methodology: Methodology for first Engineering Script Language (ESL) knowledge base [PDF]
The primary goal of reusing software components is that software can be developed faster, cheaper and with higher quality. Though, reuse is not automatic and can not just happen. It has to be carefully engineered.
Izygon, Michel E., Peeris, Kumar
core +1 more source
TimeMachine: Timeline Generation for Knowledge-Base Entities
, 2015 We present a method called TIMEMACHINE to generate a timeline of events and relations for entities in a knowledge base. For example for an actor, such a timeline should show the most important professional and personal milestones and relationships such ...
Baeza-Yates R. A. +8 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Knowledge Acquisition for Diagnosis of Skin Diseases as an Initial Platform for an Expert System
Journal of Health Management & Informatics, 2018 Background: The diagnosis of skin diseases, especially in patients suffering from more than one disease or having similar symptoms, is very complex and access to the knowledge of skin diseases makes the design of an expert system easier.
Fatemeh Rangraz Jeddi +2 more
doaj
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Planetary Defense Mitigation Gateway: A One-Stop Gateway for Pertinent PD-Related Contents
Data, 2019 Planetary Defense (PD) has become a critical effort of protecting our home planet by discovering potentially hazardous objects (PHOs), simulating the potential impact, and mitigating the threats.
Ishan Shams +13 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
ByNowLife: A Novel Framework for OWL and Bayesian Network Integration
Information, 2019 An ontology-based system can currently logically reason through the Web Ontology Language Description Logic (OWL DL). To perform probabilistic reasoning, the system must use a separate knowledge base, separate processing, or third-party applications ...
Foni A. Setiawan +2 more
doaj +1 more source