Results 41 to 50 of about 1,501,270 (269)

Knowledge‐based systems: a re‐evaluation [PDF]

Journal of Knowledge Management, 2006
PurposeThe goal of this paper is to re‐evaluate the role of knowledge‐based systems (KBS) in knowledge management (KM). While knowledge‐based systems and expert systems were widely used in the past, they have now fallen from favor and are largely ignored in the knowledge management literature.
Abdullah, Mohd Syazwan, Kimble, Chris, Benest, Ian, Paige, Richard   +3 more
openaire   +3 more sources

A Multi-functional Information Leitstand for Top-Management - A Proposal [PDF]

Journal of Systemics, Cybernetics and Informatics, 2006
Demand pull and technology push as well as recent initiatives by market-leading software companies indicate that the science of information systems needs to take a new run at the upper layers of management. One of the reasons is the growing importance of
Peter Mertens, Marco C. Meier, Martin Stöẞlein, Sandra Gilleẞen   +3 more
doaj  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Development and deployment of a digital twin for monitoring of an adaptive clamping mechanism, used for high performance composite machining

IET Collaborative Intelligent Manufacturing, 2022
In this work, we present a cloud‐based digital twin for monitoring of a clamping technology for machining of composite parts. Supporting large and/or freeform composite parts is crucial to avoid bending during drilling.
Sam Weckx, Bart Meyers, Jeroen Jordens, Steven Robyns, Jonathan Baake, Pieter Lietaert, Roeland DeGeest, Davy Maes   +7 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Learning Task Knowledge from Dialog and Web Access

Robotics, 2015
We present KnoWDiaL, an approach for Learning and using task-relevant Knowledge from human-robot Dialog and access to the Web. KnoWDiaL assumes that there is an autonomous agent that performs tasks, as requested by humans through speech.
Vittorio Perera, Robin Soetens, Thomas Kollar, Mehdi Samadi, Yichao Sun, Daniele Nardi, René van de Molengraft, Manuela Veloso   +7 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Connected, digitalized wire arc additive manufacturing: utilizing data in the internet of production to enable industrie 4.0

Scientific Reports
This work explores the potential of connected, digitalized Wire Arc Additive Manufacturing (WAAM) within the framework of Industrie 4.0, analyzing it through distinct process layers: workpiece, assembly, and product. Each layer presents unique timeframes
Samuel Mann, Jan Pennekamp, Muzaffer Ay, Mohamed Behery, Lukas Oster, Benjamin Ebert, Rahul Sharma, Dirk Abel, Gerhard Lakemeyer, Uwe Reisgen, Klaus Wehrle   +10 more
doaj   +1 more source

Intelligent System for Evaluating the Level of Formation of Professional Competencies of Students

IEEE Access, 2020
This paper proposes the creation of an intelligent system for assessing the levels of professional competencies of students in e-learning. Mathematical models and methods for assessing the formation of professional competencies of students at the level ...
A. Barlybayev, Z. Kaderkeyeva, G. Bekmanova, A. Sharipbay, A. Omarbekova, S. Altynbek   +5 more
doaj   +1 more source