Results 41 to 50 of about 6,326,238 (294)

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

A Multi-functional Information Leitstand for Top-Management - A Proposal [PDF]

Journal of Systemics, Cybernetics and Informatics, 2006
Demand pull and technology push as well as recent initiatives by market-leading software companies indicate that the science of information systems needs to take a new run at the upper layers of management. One of the reasons is the growing importance of
Peter Mertens, Marco C. Meier, Martin Stöẞlein, Sandra Gilleẞen   +3 more
doaj  

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian, Robert U. Newton, Dennis R. Taaffe, Nicholas G. Gottardo, Santosh Valvi, Carolyn J. Peddle‐McIntyre, Jodie Cochrane Wilkie, Daniel A. Galvão   +7 more
wiley   +1 more source

Development and deployment of a digital twin for monitoring of an adaptive clamping mechanism, used for high performance composite machining

IET Collaborative Intelligent Manufacturing, 2022
In this work, we present a cloud‐based digital twin for monitoring of a clamping technology for machining of composite parts. Supporting large and/or freeform composite parts is crucial to avoid bending during drilling.
Sam Weckx, Bart Meyers, Jeroen Jordens, Steven Robyns, Jonathan Baake, Pieter Lietaert, Roeland DeGeest, Davy Maes   +7 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Intelligent System for Evaluating the Level of Formation of Professional Competencies of Students

IEEE Access, 2020
This paper proposes the creation of an intelligent system for assessing the levels of professional competencies of students in e-learning. Mathematical models and methods for assessing the formation of professional competencies of students at the level ...
A. Barlybayev, Z. Kaderkeyeva, G. Bekmanova, A. Sharipbay, A. Omarbekova, S. Altynbek   +5 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Connected, digitalized wire arc additive manufacturing: utilizing data in the internet of production to enable industrie 4.0

Scientific Reports
This work explores the potential of connected, digitalized Wire Arc Additive Manufacturing (WAAM) within the framework of Industrie 4.0, analyzing it through distinct process layers: workpiece, assembly, and product. Each layer presents unique timeframes
Samuel Mann, Jan Pennekamp, Muzaffer Ay, Mohamed Behery, Lukas Oster, Benjamin Ebert, Rahul Sharma, Dirk Abel, Gerhard Lakemeyer, Uwe Reisgen, Klaus Wehrle   +10 more
doaj   +1 more source