Results 91 to 100 of about 5,810,256 (329)
Interpretable Question Answering on Knowledge Bases and Text [PDF]
Annual Meeting of the Association for Computational Linguistics, 2019 Interpretability of machine learning (ML) models becomes more relevant with their increasing adoption. In this work, we address the interpretability of ML based question answering (QA) models on a combination of knowledge bases (KB) and text documents ...
Alona Sydorova +2 more
semanticscholar +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A logical specification language for ontologies in the system “Binary Model of Knowledge”
Open Engineering, 2018 We describe the language LLS-1 for logical specifying ontologies written in “Binary Model of Knowledge” (BMK). BMK is the system intended for specifying heavy-weight ontologies by means of conceptual-type languages. The language LLS-1 has a user-friendly
Plesniewicz Gerald +2 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
European Journal of Spatial DevelopmentSmall towns have become increasingly important to research in recent years. However, researchers have largely ignored both the reciprocal economic-functional linkages between large cities and small towns in agglomerations and the spatial patterns of ...
Madeleine Wagner
doaj +3 more sources
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Data optimization for the knowledge bases in the oil and gas Monitoring-While-Drilling (MWD) Systems [PDF]
, 2023 Liudmyla Poteriailo +3 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Knowledge bases and software support for variant interpretation in precision oncology. [PDF]
Brief Bioinform, 2021 Borchert F +16 more
europepmc +2 more sources