Results 21 to 30 of about 1,199,057 (174)
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Plan Synthesis for Knowledge and Action Bases [PDF]
, 2016 We study plan synthesis for a variant of Knowledge and Action Bases (KABs), a rich, dynamic framework, where states are description logic (DL) knowledge bases (KBs) whose extensional part is manipulated by actions that possibly introduce new objects from
Calvanese, Diego +3 more
core
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Knowledge structure, knowledge granulation and knowledge distance in a knowledge base [PDF]
International Journal of Approximate Reasoning, 2009 AbstractOne of the strengths of rough set theory is the fact that an unknown target concept can be approximately characterized by existing knowledge structures in a knowledge base. Knowledge structures in knowledge bases have two categories: complete and incomplete. In this paper, through uniformly expressing these two kinds of knowledge structures, we
Jiye Liang, Yuhua Qian, Chuangyin Dang
openaire +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
miRo: a miRNA knowledge base [PDF]
Database, 2009 miRò is a web-based knowledge base that provides users with miRNA-phenotype associations in humans. It integrates data from various online sources, such as databases of miRNAs, ontologies, diseases and targets, into a unified database equipped with an intuitive and flexible query interface and data mining facilities.
A. Giudice +9 more
openaire +3 more sources
Splitting and Updating Hybrid Knowledge Bases (Extended Version)
, 2011 Over the years, nonmonotonic rules have proven to be a very expressive and useful knowledge representation paradigm. They have recently been used to complement the expressive power of Description Logics (DLs), leading to the study of integrative formal ...
Leite, João +2 more
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Knowledge-based Configuration [PDF]
JUCS - Journal of Universal Computer Science, 2020 Felfernig,Alexander, Tiihonen,Juha
openaire +4 more sources