Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
Web-Based Knowledge Extraction and the Cognitive Characterization of Cultural Groups
, 2011 The advent of Web 2.0 has provided new opportunities for cultural analysts to understand more about the cognitive characteristics of cultural groups. In particular, user-contributed content provides important indications as to the beliefs, attitudes and ...
Sieck, Winston R +3 more
core +1 more source
Regional Strategic Analysis and Knowledge Support System (ReSAKSS)
, 2020 Regional strategic analysis and knowledge support system (ReSAKSS) is a Africa-focused database nodes that compile, analyze, and disseminate data, information, and tools to help design, implement, monitor, and evaluate rural development strategies.Non ...
Regional Strategic Analysis and Knowledge Support System (ReSAKSS)
core
Knowledge extraction and transfer in data-driven fracture mechanics. [PDF]
Proc Natl Acad Sci U S A, 2021 Liu X +4 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
Disease- and Drug-Related Knowledge Extraction for Health Management from Online Health Communities Based on BERT-BiGRU-ATT. [PDF]
Int J Environ Res Public Health, 2022 Zhang Y, Li X, Yang Y, Wang T.
europepmc +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Knowledge extraction from pointer movements and its application to detect uncertainty. [PDF]
Heliyon, 2021 Cepeda C +4 more
europepmc +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Efficient Reinforcement Learning from Demonstration via Bayesian Network-Based Knowledge Extraction. [PDF]
Comput Intell Neurosci, 2021 Zhang Y +5 more
europepmc +1 more source