Results 181 to 190 of about 803,882 (321)

Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria

FEBS Open Bio, EarlyView.
The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao, Takato Ozaki, Hirofumi Fukuda, Yu Kanesaki, Munehiko Asayama   +4 more
wiley   +1 more source

Untangle the KNOT: Interweaving Conflicting Knowledge and Reasoning Skills in Large Language Models [PDF]

arXiv
Providing knowledge documents for large language models (LLMs) has emerged as a promising solution to update the static knowledge inherent in their parameters. However, knowledge in the document may conflict with the memory of LLMs due to outdated or incorrect knowledge in the LLMs' parameters. This leads to the necessity of examining the capability of
arxiv  

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Clinical knowledge extraction via sparse embedding regression (KESER) with multi-center large scale electronic health record data. [PDF]

NPJ Digit Med, 2021
Hong C, Rush E, Liu M, Zhou D, Sun J, Sonabend A, Castro VM, Schubert P, Panickan VA, Cai T, Costa L, He Z, Link N, Hauser R, Gaziano JM, Murphy SN, Ostrouchov G, Ho YL, Begoli E, Lu J, Cho K, Liao KP, Cai T, VA Million Veteran Program.   +23 more
europepmc   +1 more source

Multistage Fuzzy Inference for Blood Pressure Control in Anesthesia and Knowledge Extraction from Time-Series Clinical Data by GA

, 2002
Hisakazu Ogura, Hidetoshi UKAI, Haruhiko Shirai, Junji Nishino, Tomohiro Odaka, Shuzo Oshita   +5 more
openalex   +2 more sources

Utilization of external knowledge to support answer extraction from restricted document using logical reasoning [PDF]

, 2008
Rabiah Abdul Kadir, Tengku Mohd Tengku Sembok, B. Z. Halimah   +2 more
openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Automated knowledge extraction from polymer literature using natural language processing. [PDF]

iScience, 2021
Shetty P, Ramprasad R.
europepmc   +1 more source

Incorporating Generic and Specific Prior Knowledge in a Multiscale Phase Field Model for Road Extraction From VHR Images [PDF]

, 2008
Ting Peng, Ian H. Jermyn, V. Prinet, Josiane Zerubia   +3 more
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source