Results 61 to 70 of about 8,023,305 (265)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Research on Service Discovery Methods Based on Knowledge Graph
IEEE Access, 2020 Service discovery is one of the main goals of a service-oriented architecture, helping to discover complex applications. Knowledge graph is a cross-cutting research hotspot in the fields of computer, knowledge engineering and information science.
Li Guodong +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Semantic Structure based Query Graph Prediction for Question Answering over Knowledge Graph
, 2022 Building query graphs from questions is an important step in complex question answering over knowledge graph (Complex KGQA). In general, a question can be correctly answered if its query graph is built correctly and the right answer is then retrieved by ...
Li, Mingchen
core +1 more source
Graph Attention Networks With Local Structure Awareness for Knowledge Graph Completion
IEEE Access, 2020 Graph neural networks have been proven to be very effective for representation learning of knowledge graphs. Recent methods such as SACN and CompGCN, have achieved the most advanced results in knowledge graph completion.
Kexi Ji, Bei Hui, Guangchun Luo
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
PEMBENTUKAN WORD GRAPH PREPOSISI BAHASA INDONESIA MENGGUNAKAN METODE KNOWLEDGE GRAPH [PDF]
, 2015 Knowledge Graph (KG) is a new method of knowledge representation, belongs to the category of semantics network. In principle, the composition of a knowledge graph is including concept and relationship. In KG we can expressed the meaning of word with word
Anggraeni, Wulan
core +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
A Quick Prototype for Assessing OpenIE Knowledge Graph-Based Question-Answering Systems
Information, 2023 Due to the rapid growth of knowledge graphs (KG) as representational learning methods in recent years, question-answering approaches have received increasing attention from academia and industry.
Giuseppina Di Paolo +2 more
doaj +1 more source