Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
From Synergy to Strain: Exploring the Psychological Mechanisms Linking Employee-AI Collaboration and Knowledge Hiding. [PDF]
Li YB, Liao TH, Tsai CH, Wu TJ.
europepmc +1 more source
Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang +17 more
wiley +1 more source
Why do knowledge workers choose knowledge hiding: the mediating role of perceived stress. [PDF]
Bai Y, Xiao Y.
europepmc +1 more source
Temporary Team Performance and Knowledge Hiding: Mediated by Interpersonal Mistrust. [PDF]
Miao Y, Qi N, Liu E, Zhai P.
europepmc +1 more source
SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He +5 more
wiley +1 more source
Managing knowledge hiding behaviors in Chinese enterprises: the mediating effects of power dynamics losses. [PDF]
Liu Y, Liu C, Spolaor R, Chen S.
europepmc +1 more source
The impact of entrepreneurial team psychological capital on innovation performance: The mediating role of knowledge sharing and knowledge hiding. [PDF]
Chen M, Mi X, Xue J, Li Y, Shi J.
europepmc +1 more source

