Results 71 to 80 of about 4,132,791 (270)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Analyzing the Improvement Policies of Knowledge Management by Using System Dynamics

Iranian Journal of Information Processing & Management, 2018
Knowledge management is one of the main driver of innovation in organizations that acts in a set form of processes and technology. In different organizations the trend of knowledge process maturity has its specific dynamics.
Elahe Fayyaz, Seyed Hamed Moosavirad
doaj  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Nurses' experiences of delirium and how to identify delirium—A qualitative study

Nursing Open, 2021
Aim Delirium is a serious, acute medical condition which places a heavy burden on the patient, his or her family and healthcare professionals. There have been only a limited number of studies to explore nurses' experiences of delirium and how delirium is
Ann Karin Helgesen, Yassin Husein Adan, Caroline Dybvik Bjørglund, Chris Weberg‐Haugen, Mona Johannessen, Kristine Åsmul Kristiansen, Elisabeth Vasskog Risan, Ma Lorinda Relusco, Heidi Marie Skaarer‐Heen, Tina Sofie Sørensen, Linea Vedå, Vigdis Abrahamsen Grøndahl   +11 more
doaj   +1 more source

Knowledge engineering techniques for utility identification

Acta Psychologica, 1988
Abstract In this paper multiattribute decision making is discussed in terms of decision-making knowledge. Special emphasis is on identification (measurement) and verification of utility functions, and their use for evaluation of alternatives and explanation of evaluation results.
V. Rajkovič, M. Bohanec, V. Batagelj
openaire   +1 more source

Interaction of knowledge sources in spoken word identification [PDF]

Journal of Memory and Language, 1985
A gating technique was used in two studies of spoken word identification that investigated the relationship between the available acoustic-phonetic information in the speech signal and the context provided by meaningful and semantically anomalous sentences. The duration of intact spoken segments of target words and the location of these segments at the
Aita, Salasoo, David B, Pisoni
openaire   +2 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Location of knowledge about consumers

Contemporary Economy, 2012
Nowadays, knowledge about customers is the most valuable asset for any enterprise.Using it, organizations can more effectively increase customer loyalty and their value to the company.
Dorota Buchnowska
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source