Results 71 to 80 of about 1,136,160 (329)

Strategic Alignment Approach and Balanced Maturity in Effective Implementation of Knowledge Management [PDF]

open access: yesپژوهش‌های مدیریت عمومی, 2016
Establishment ofknowledge management need alignmentwith important components of domestic andforeign organizationsand balanced advancing of these components fromstage to stage.An integrated model of organizational maturitywith the models of effective ...
Noormohammad Yaghoubi   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Integrated Knowledge Management Maturity Model

open access: yesZagreb international review of economics & business, 2008
Although many organisations worldwide are introducing knowledge management (KM) practices, there is no generally acknowledged methodology for assessing where the organisation stands, compared to its competitors. Several knowledge management maturity models have been developed, but they are so heterogeneous that the practice is evidently calling for a ...
Rašula, Jelena   +2 more
openaire   +4 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Maintenance management based on organization maturity level [PDF]

open access: yes, 2012
This article aims to discuss the management processes of the maintenance function of a company depending on the degree of maturity of the organization in connection with the maintenance, redefining training strategies, collection and analysis of failures,
Figueiredo, Danielle   +2 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Outsourcing and acquisition models comparison related to IT supplier selection decision analysis [PDF]

open access: yes, 2012
This paper presents a comparison of acquisition models related to decision analysis of IT supplier selection. The main standards are: Capability Maturity Model Integration for Acquisition (CMMI-ACQ), ISO / IEC 12207 Information Technology / Software Life
Calvo-Manzano Villalon, Jose Antonio   +1 more
core   +1 more source

A strategic niche management approach for shaping bio-based economy in Europe [PDF]

open access: yes, 2018
The goal of this paper is to investigate the transition towards a bio-based economy as part of a broader sustainable transition in Europe. To analyse the challenges and opportunities associated with the bio-based economy, we applied the Strategic Niche ...
Tani, Almona
core   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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