Results 31 to 40 of about 633,162 (316)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Collecting and using social needs data in health settings: a systematic review of the literature on health service utilization and costs

BMC Health Services Research
Background Social determinants of health significantly influence health outcomes and contribute to health inequities across populations. Systematic and routine collection of social needs data and its use to inform interventions within healthcare settings
Mélanie Ann Smithman, Oluwasegun J. Ogundele, Laure Perrier, Menna Komeiha, Iryna Artyukh, Paras Kapoor, Andrew D. Pinto   +6 more
doaj   +1 more source

Knowledge mapping as a tecnique to support knowledge translation

Bulletin of the World Health Organization, 2006
This paper explores the possibility of integrating knowledge mapping into a conceptual framework that could serve as a tool for understanding the many complex processes, resources and people involved in a health system, and for identifying potential gaps within knowledge translation processes in order to address them.
Ebener S, Khan A, Shademani R, Compernolle L, Beltran M, Lansang MA, Lippman M   +6 more
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Cardiovascular disease essential medicines listing by countries: changes over time and association with health outcomes

BMC Cardiovascular Disorders
Background Since national essential medicine lists guide the procurement of medicines for populations in many countries, and cardiovascular diseases are the leading cause of death globally, including cardiovascular medicines on these lists can ...
Camila Heredia, Moizza Zia Ul Haq, Adelaide Buadu, Amal Rizvi, Aine Workentin, Navindra Persaud   +5 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Interventions in ambulatory healthcare settings to reduce social isolation among adults aged 18–64: a systematic review

BJGP Open
Background: Social isolation is associated with increased all-cause and premature mortality, poor chronic disease management, and mental health concerns.
Kavya Anchuri, Liane Steiner, Roxana Rabet, Amy Craig-Neil, Ellah San Antonio, Oluwasegun Jko Ogundele, Melanie Seabrook, Ceinwen Pope, Serina Dai, Andree Schuler, Carolyn Ziegler, Andrew David Pinto   +11 more
doaj   +1 more source

Impact of experienced HIV stigma on health is mediated by internalized stigma and depression: results from the people living with HIV stigma index in Ontario

BMC Public Health, 2021
Background Experiences of HIV stigma remain prevalent across Canada, causing significant stress and negatively affecting the health and wellbeing of people living with HIV.
Jason M. Lo Hog Tian, James R. Watson, Francisco Ibáñez-Carrasco, Billy Tran, Janet A. Parsons, Robert G. Maunder, Kiffer G. Card, Stefan Baral, Christian Hui, Anthony R. Boni, Monisola Ajiboye, Joanne D. Lindsay, Sean B. Rourke, The Ontario HIV Stigma Index Team   +13 more
doaj   +1 more source

Exploring COVID-19 vaccine uptake, confidence and hesitancy among people experiencing homelessness in Toronto, Canada: protocol for the Ku-gaa-gii pimitizi-win qualitative study

BMJ Open, 2022
Introduction People experiencing homelessness are at high risk for COVID-19 and poor outcomes if infected. Vaccination offers protection against serious illness, and people experiencing homelessness have been prioritised in the vaccine roll-out in ...
Tara Kiran, Lucie Richard, Stephen W Hwang, Rosane Nisenbaum, Aaron Orkin, Ruby Sniderman, Michael Liu, Allison Dyer, Cheryl Pedersen, Olivia Spandier, Jesse I R Jenkinson, Evie Gogosis, Tadios Tibebu, Frank Crichlow, Naomi Thulien, Jolen Kayseas   +15 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source