Results 91 to 100 of about 5,431,838 (297)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
HOW TO MEASURE THE ECONOMY BASED OF KNOWLEDGE : A SHORT REVIEW [PDF]
Management Intercultural, 2013 In this work was outlined essence of the knowledge economy and characterized its basic components. The objectives in this article were based on synthesis the role of the knowledge economy. These studies have a high degree of novelty and complexity of the
Aurelia TURCAN
doaj
Measuring Accuracy of Triples in Knowledge Graphs [PDF]
, 2017 An increasing amount of large-scale knowledge graphs have been constructed in recent years. Those graphs are often created from text-based extraction, which could be very noisy. So far, cleaning knowledge graphs are often carried out by human experts and thus very inef- ficient.
Shuangyan Liu +2 more
openaire +2 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Impact of a Science Methods Course on Pre-Service Elementary Teachers\u27 Knowledge and Confidence of Teaching with Scientific Inquiry and Problem-Based Learning [PDF]
, 2015 The purpose of this study was to measure the impact of an elementary science methods course on pre-service teachers\u27 knowledge and confidence of teaching with inquiry and problem-based instructional strategies.
Spencer, T. L. +2 more
core +1 more source
Measure and Probability in Cosmology
, 2012 General relativity has a Hamiltonian formulation, which formally provides a canonical (Liouville) measure on the space of solutions. In ordinary statistical physics, the Liouville measure is used to compute probabilities of macrostates, and it would seem
Joshua S. Schiffrin +4 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Constructing a measure of industry-specific human capital using Tobin's q theory [PDF]
In this paper, we develop a measure of industry specific human capital using the Tobin's q theory. The measure is derived from a structural model of heterogeneous knowledge labor, which is homogeneous physical labor embodied with industry specific human ...
Kam-Ki Tang, Yi-Ping Tseng
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
How to Measure Procedural Knowledge for Solving Biodiversity and Climate Change Challenges
Education Sciences, 2018 To cope with biodiversity and climate change challenges, Education for Sustainable Development (ESD) needs to emphasize knowledge that considers multiple perspectives.
Lisa Richter-Beuschel +2 more
doaj +1 more source