Results 101 to 110 of about 5,431,838 (297)

Measuring Disagreement Among Knowledge Bases [PDF]

open access: yesEasyChair Preprints, 2018
When combining beliefs from different sources,<br/>often not only new knowledge but also conflicts arise.<br/>In this paper, we investigate how we can measure the disagreement<br/>among sources. We start our investigation with disagreement measures<br/>that can be induced from inconsistency measures in an automated way.<br ...
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Development of a measure of knowledge use by stakeholders in rehabilitation technology

open access: yesSAGE Open Medicine, 2014
Objectives: Uptake of new knowledge by diverse and diffuse stakeholders of health-care technology innovations has been a persistent challenge, as has been measurement of this uptake.
Vathsala I Stone   +5 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Does it Matter What We Measure? Domain-specific Professional Knowledge of Physics Teachers

open access: yesSchweizerische Zeitschrift für Bildungswissenschaften, 2018
Can we be confident that extensively validated tests for teachers on their professional knowledge actually measure what matters for effective teaching? This study investigated the relations between physics teachers’ domain-specific professional knowledge,
Eva Cauet   +3 more
doaj   +1 more source

Knowledge, networks of cities and growth in regional urban systems: theory, measurement and policy implications [PDF]

open access: yes
The objective of this paper is to measure the impact of different kinds of knowledge and external economies on the urban growth in an intraregional network of cities. The paper is divided in five sections.
Joan Trullén, Rafael Boix
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Knowledge-based accuracy and similarity measures in Interval-valued Neutrosophic context and their applications in wastewater treatment method decision-making

open access: yesFranklin Open
The role of Interval-valued Neutrosophic Knowledge measures and Entropy measures is crucial. The main objective of this manuscript is to study the knowledge measures that apply to decision-making problems for interval-valued neutrosophic sets.
Amandeep Singh, Satish Kumar
doaj   +1 more source

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