Results 121 to 130 of about 5,431,838 (297)
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
MEASURING CONTAGION WITH A BAYESIAN TIME-VARYING COEFFICIENT MODEL [PDF]
We propose to use a time-varying coefficient model to measure contagion. The proposed measure works in the joint presence of heteroskedasticity and omitted variables. It requires knowledge of the source of the crisis but not its timing.
Alessandro Rebucci
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Recovering an homogeneous polynomial from moments of its level set
, 2012 Let $K:={x: g(x)\leq 1}$ be the compact sub-level set of some homogeneous polynomial $g$. Assume that the only knowledge about $K$ is the degree of $g$ as well as the moments of the Lebesgue measure on $K$ up to order 2d.
Lasserre, Jean
core +1 more source
Measuring Knowledge for Recognition and Knowledge Entropy
, 2018 People employ their knowledge to recognize things. This paper is concerned with how to measure people's knowledge for recognition and how it changes. The discussion is based on three assumptions. Firstly, we construct two evolution process equations, of which one is for uncertainty and knowledge, and the other for uncertainty and ignorance.
openaire +2 more sources
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
The link between the quality of knowledge management and financial performance – The case of Croatia [PDF]
The paper investigates the link between the quality of knowledge management and financial performance of an organization, using the data from the research conducted in Croatia.
Maja Vidović
core
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
A Semantic Similarity Measure for Expressive Description Logics
, 2009 A totally semantic measure is presented which is able to calculate a similarity value between concept descriptions and also between concept description and individual or between individuals expressed in an expressive description logic.
d'Amato, Claudia +2 more
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