Results 31 to 40 of about 148,575 (264)

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter Lange, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

The next phase of healthcare improvement: what can we learn from social movements? [PDF]

, 2004
To date, improvement in health care has relied mainly on a "top down" programme by programme approach to service change and development. This has spawned a multitude of different and often impressive improvement schemes and activities.
Bate, SP, Bevan, H, Robert, G
core   +1 more source

Mobilising research knowledge in education

London Review of Education, 2011
The field of knowledge mobilisation (KM) addresses the multiple ways in which stronger connections can be made between research, policy and practice. This paper reviews the current situation around knowledge mobilisation in education. It addresses changing understandings of KM, considers some of the main issues in conducting empirical research in the ...
openaire   +1 more source

Information Transmission Strategies for Self‐Organized Robotic Aggregation

Advanced Robotics Research, EarlyView.
In this review, we discuss how information transmission influences the neighbor‐based self‐organized aggregation of swarm robots. We focus specifically on local interactions regarding information transfer and categorize previous studies based on the functions of the information exchanged.
Shu Leng, Zihan Li, Yifeng Shao, Jinhao Liu, Li Yu, Shuguang Li   +5 more
wiley   +1 more source

Media transformation and new practices of citizenship: the example of environmental activism in South Durban [PDF]

, 2002
South African media and telecommunications have been fundamentally restructured in the last decade. Corporate unbundling and black economic empowerment have transformed the ownership of broadcasting, print media, publishing, and telecommunications; new ...
Barnett, Clive
core  

Building Biodiversity Knowledge: Mobilising Citizen Science

, 2023
AbstractSouth Africa enjoys a long history of biological exploration and documentation. However, until recently, much of this information remained inaccessible in herbaria, museums and libraries. During the 1970s and ‘80s, a strong tradition of cooperative research led to the rapid expansion of biodiversity knowledge through multidisciplinary biome and
openaire   +1 more source

A Soft Robotic Device for Targeted Massage Therapy of Residual Limbs

Advanced Robotics Research, EarlyView.
Residual limb edema after amputation can hinder recovery and delay prosthetic fitting. This study presents a soft‐robotic wearable device that delivers sequential compression through pneumatic McKibben actuators. By replicating the principles of manual lymphatic drainage, the device generates controlled mechanotherapeutic pressure patterns, providing a
Maria Grazia Polizzotto, Alessio Capecchi, Maartje Van der Lingen, Emanuele Gruppioni, Arianna Menciassi, Linda Paternò   +5 more
wiley   +1 more source

Developing and implementing an integrated delirium prevention system of care:a theory driven, participatory research study [PDF]

, 2013
Background: Delirium is a common complication for older people in hospital. Evidence suggests that delirium incidence in hospital may be reduced by about a third through a multi-component intervention targeted at known modifiable risk factors.
A Edlund, A McIntyre, AE Powell, C May, C May, CV Lukas, DK Kiely, DL Fixsen, DL Leslie, DL Leslie, E Marcantonio, EH Bradley, EM Eeles, ER Marcantonio, ER Marcantonio, ER Marcantonio, FH Rubin, Francine Cheater, GK SteelFisher, GS Duppils, HC Kaplan, J Corbin, J Day, J McCusker, J Ovretveit, J Witlox, JA Rizzo, Jane Smith, John B Young, John Green, K Milisen, K Milisen, KH Pitkala, LJ Damschroder, LJ Young, Mary Godfrey, MG Cole, P Bate, P Galanakis, P Hawe, P Hawe, P Pronovost, P Williams-Russo, R Grol, Royal College of Psychiatrists, S Dahlke, Sharon K Inouye, SK Inouye, SK Inouye, SK Inouye, SK Inouye, SK Inouye, ST O'Keeffe, T Greenhalgh, Y Gustafson   +54 more
core   +1 more source

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

Advanced Science, EarlyView.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou, Yinghua Ma, Qin Liu, Dingling Ma, Yuxin Tong, Lili Xu, Xiaolong Chu, Jingzhou Wang, Maodi Liang, Mengyuan Zhao, Huizi Zhang, Yurui Su, Jianxin Xie, Cuizhe Wang, Jun Zhang   +14 more
wiley   +1 more source

Mobilising knowledge in complex health systems: a call to action [PDF]

Evidence and Policy, 2017
Worldwide, policymakers, health system managers, practitioners and researchers struggle to use evidence to improve policy and practice. There is growing recognition that this challenge relates to the complex systems in which we work. The corresponding increase in complexity-related discourse remains primarily at a theoretical level.
Holmes, Bev J., Best, Allan, Davies, Huw, Hunter, David, Kelly, Michael P., Marshall, Martin, Rycroft-Malone, Joanne   +6 more
openaire   +4 more sources