Results 51 to 60 of about 9,680,994 (286)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Active Knowledge Models and Enterprise Knowledge Management [PDF]

, 2003
We present in this paper a novel approach for integrating enterprise modeling and knowledge management in dynamic networked organisations. The approach is based on the notion of active knowledge models (AKMTM). An AKM is a visual model of enterprise aspects that can be viewed, traversed, analysed, simulated, adapted and executed by industrial users. To
Frank M. Lillehagen, John Krogstie
openaire   +2 more sources

Regional Strategic Analysis and Knowledge Support System (ReSAKSS)

, 2020
Regional strategic analysis and knowledge support system (ReSAKSS) is a Africa-focused database nodes that compile, analyze, and disseminate data, information, and tools to help design, implement, monitor, and evaluate rural development strategies.Non ...
Regional Strategic Analysis and Knowledge Support System (ReSAKSS)
core  

A method for constructing a knowledge graph of coal mine roof disaster prevention and control

Gong-kuang zidonghua
At present, the decision-making of coal mine roof disaster prevention and control measures and the analysis of accident causes mainly rely on manual experience, and the level of intelligence is relatively low.
LUO Xiangyu, DU Hao, HUA Ying, XIE Panshi, LYU Wenyu   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Respiratory Rate as a Predictor of Weaning Failure from Mechanical Ventilation

Brazilian Journal of Anesthesiology, 2013
Background and objective: There is not an ideal predictor of weaning from mechanical ventilation (MV). In a large meta-analysis, despite methodological limitations, respiratory rate (RR) was considered a promising predictor.
Emídio Jorge Santos Lima
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

A Comparison between APGAR Scores and Birth Weight in Infants of Addicted and Non-Addicted Mothers [PDF]

Addiction and Health, 2011
Background: Addiction in pregnant women causes complications such as abortion, asphyxia and cerebral and physical problems. APGAR score assesses vital signs and birth weight and represents the physical and brain growth of newborns.
Esmat Rahi, Mohammad Reza Baneshi, Ehsan Mirkamandar, Saiedeh Haji Maghsoudi, Azam Rastegari   +4 more
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source