Results 31 to 40 of about 2,675,823 (174)
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Proceedings of the Eighteenth International Conference on Principles of Knowledge Representation and Reasoning [PDF]
, 2021 Thomas Ågotnes, Yì Wáng
openalex +1 more source
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
Data‐driven performance metrics for neural network learning
International Journal of Adaptive Control and Signal Processing, EarlyView., 2023 Summary Effectiveness of data‐driven neural learning in terms of both local mimima trapping and convergence rate is addressed. Such issues are investigated in a case study involving the training of one‐hidden‐layer feedforward neural networks with the extended Kalman filter, which reduces the search for the optimal network parameters to a state ...
Angelo Alessandri +2 more
wiley +1 more source
Reasoning for Moving Blocks Problem: Formal Representation and Implementation [PDF]
arXiv, 2013 The combined approach of the Qualitative Reasoning and Probabilistic Functions for the knowledge representation is proposed. The method aims at represent uncertain, qualitative knowledge that is essential for the moving blocks task's execution. The attempt to formalize the commonsense knowledge is performed with the Situation Calculus language for ...
arxiv
Combining Representation Learning and Logical Rule Reasoning for Knowledge Graph Inference [PDF]
, 2022 Yizhou Sun
openalex +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Combining Ontologies with Correspondences and Link Relations: The E-SHIQ Representation Framework [PDF]
arXiv, 2013 Combining knowledge and beliefs of autonomous peers in distributed settings, is a ma- jor challenge. In this paper we consider peers that combine ontologies and reason jointly with their coupled knowledge. Ontologies are within the SHIQ fragment of Description Logics. Although there are several representation frameworks for modular Description Log- ics,
arxiv
Proceedings of the Twentieth International Conference on Principles of Knowledge Representation and Reasoning [PDF]
, 2023 Carlos Aguilera-Ventura +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source