Results 141 to 150 of about 2,109,221 (325)

Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib

ACR Open Rheumatology, EarlyView.
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi, Ennio Giulio Favalli, Gabriella Maioli, Elena Agape, Marzia Rossato, Matteo Paini, Adriana Severino, Barbara Vigone, Martina Biggioggero, Elena Trombetta, Roberto Caporali, Lorenzo Beretta   +11 more
wiley   +1 more source

A Framework for a New Paradigm of Opioid Drug Tapering Using Adjunct Drugs

Substance Abuse and Rehabilitation
Michael A Veronin,1 Justin P Reinert2 1Department of Pharmaceutical Sciences and Health Outcomes The University of Texas at Tyler Ben and Maytee Fisch College of Pharmacy, Tyler, TX, USA; 2Department of Pharmacy Practice The University of Toledo College ...
Veronin MA, Reinert JP
doaj  

Synthesizing evidence and identifying knowledge gaps in the role of swine in Japanese encephalitis virus transmission: a rapid systematic review of the literature

Frontiers in Sustainable Food Systems
The United States is considered a susceptible region with great potential for the introduction of the Japanese encephalitis virus (JEV) given the presence of competent mosquito vector species, susceptible maintenance avian hosts, large populations of ...
V. Horton, C. J. Hanthorn, A. L. Dixon, S. E. Edache, A. Thackrah, D. Mitzel, L. Noronha, L. W. Cohnstaedt, V. R. Brown, C. Mire, N. Cernicchiaro   +10 more
doaj   +1 more source

Machine learning on small size samples: A synthetic knowledge synthesis. [PDF]

Sci Prog, 2022
Kokol P, Kokol M, Zagoranski S.
europepmc   +1 more source

A knowledge synthesis of patient and public involvement in clinical practice guidelines: study protocol [PDF]

, 2009
France Légaré, Antoine Boivin, Trudy van der Weijden, Christine Packenham, Sylvie Tapp, Jako Burgers   +5 more
openalex   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

The scope of health professions education requires complementary and diverse approaches to knowledge synthesis. [PDF]

Perspect Med Educ, 2022
Norman G, Sherbino J, Varpio L.
europepmc   +1 more source

A new section for IJPH: knowledge synthesis, translation and exchange [PDF]

, 2010
Louise Potvin, Thomas Abel
openalex   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

Simulation model to assess the validity of the clinical portfolio diet score used in the PortfolioDiet.app for dietary self-tracking: a secondary analysis of a randomized controlled trial in hyperlipidemic adults

Frontiers in Nutrition
IntroductionThe Portfolio Diet combines cholesterol-lowering plant foods for the management of cardiovascular disease risk. However, the translation of this dietary approach into clinical practice necessitates a user-friendly method for patients to ...
Meaghan E. Kavanagh, Meaghan E. Kavanagh, Andrea J. Glenn, Andrea J. Glenn, Andrea J. Glenn, Laura Chiavaroli, Laura Chiavaroli, Laura Chiavaroli, Gloria A. Morgan, Robert G. Josse, Robert G. Josse, Robert G. Josse, Robert G. Josse, Robert G. Josse, Vasanti S. Malik, Vasanti S. Malik, Christopher P. F. Marinangeli, Cyril W. C. Kendall, Cyril W. C. Kendall, Cyril W. C. Kendall, David J. A. Jenkins, David J. A. Jenkins, David J. A. Jenkins, David J. A. Jenkins, David J. A. Jenkins, John L. Sievenpiper, John L. Sievenpiper, John L. Sievenpiper, John L. Sievenpiper, John L. Sievenpiper   +29 more
doaj   +1 more source