Results 61 to 70 of about 3,241,412 (295)
R&D and Technology Transfer: Firm-Level Evidence from Chinese Industry [PDF]
, 2003 The capacity of developing economies to narrow the gap in living standards with the OECD nations depends critically on their ability to imitate and innovate new technologies.
Hu, Albert G. Z. +3 more
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Training Research Skills for High School Students in Vietnam: A Case Study
Vietnam Journal of EducationThis article presents a case study in Vietnam where a course on research skills was taught to outstanding high school students who are preparing to study abroad.
Hiep-Hung Pham, Linh-Chi Nguyen
doaj +1 more source
Initial teacher education 2024: why inclusion matters? [PDF]
Quality Education for All– Teacher recruitment is under pressure across England with the majority of routes into teaching facing challenges in respect to recruitment and retention. Schools are also challenged by issues of attendance, behaviour and exclusion. This paper examines
Sonia Blandford
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Knowledge Transfer via Distillation of Activation Boundaries Formed by Hidden Neurons
, 2018 An activation boundary for a neuron refers to a separating hyperplane that determines whether the neuron is activated or deactivated. It has been long considered in neural networks that the activations of neurons, rather than their exact output values ...
Choi, Jin Young +3 more
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Transferring Collective Knowledge: Collective and Fragmented Teaching and Learning in the Chinese Auto Industry [PDF]
, 2001 Collective knowledge, consisting of tacit group-embedded knowledge, is a key element of organizational capabilities. This study undertakes a multiple-case study of the transfer of collective knowledge, guided by a set of tentative constructs and ...
Anand, Jaideep +2 more
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source