MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Teleworking practice in small and medium-sized firms: Management style and worker autonomy
In an empirical study of teleworking practices amongst small and medium-sized enterprises (SMEs) in West London, organisational factors such as management attitudes, worker autonomy and employment flexibility were found to be more critical than ...
Clear, F +3 more
core +1 more source
The foreign bully, the guest and the low-income knowledge worker: performing multiple versions of whiteness in China. [PDF]
Lan S.
europepmc +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
A Practitioner’s approach to Drucker’s Knowledge- Worker Productivity in the 21st Century—a New Model (Part Two) [PDF]
This is the second article on the empirical study of Drucker’s knowledgeworker productivity. The first article examined productivity in the context of the 21st century, focusing on Drucker’s six major factors determining knowledge-worker productivity ...
Peter S WONG, Philip A NECK
doaj
Community development and working with the UCT Knowledge Co-op: a community worker's perspective
This is a summary of an interview with a community worker about her experiences of community development – and of using UCT to help her in some of this ...
UCT Knowledge Co-op
core
Health Worker Motivation in the Context of HIV Care and Treatment Challenges in Mbeya Region, Tanzania: A Qualitative Study. [PDF]
Health worker motivation can potentially affect the provision of health services. The HIV pandemic has placed additional strain on health service provision through the extra burden of increased testing and counselling, treating opportunistic infections ...
Mbilinyi, Deogratius +10 more
core +1 more source

