Results 111 to 120 of about 27,445 (253)

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić   +4 more
wiley   +1 more source

Conditional Kolmogorov complexity and universal probability

open access: yesTheoretical Computer Science, 2013
The Coding Theorem of L.A. Levin connects unconditional prefix Kolmogorov complexity with the discrete universal distribution. There are conditional versions referred to in several publications but as yet there exist no written proofs in English. Here we provide those proofs.
openaire   +6 more sources

The quantitative impact of metabolism‐inhibiting drugs on the occurrence of adverse drug reactions—A backward selection approach

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres   +8 more
wiley   +1 more source

Lost learning: Prevalence, inequalities and outcomes of internal exclusion in mainstream secondary schools

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Internal exclusion (isolation) is a behaviour management approach involving the temporary relocation of a pupil from their classroom to a designated isolation space as a consequence of disruptive behaviour. We present the first study of prevalence (i.e., what proportion of young people are isolated?), inequalities (i.e., who is more likely to ...
Emma Thornton   +3 more
wiley   +1 more source

“Bionopoly” as a Gamechanger? Effects of Gamification on Learning Success, Motivation and Activation Among Medical Students in a Biochemistry Course

open access: yesBiochemistry and Molecular Biology Education, EarlyView.
ABSTRACT Gamification is characterized by the use of gaming elements in a non‐gaming context. This concept is commonly applied in teaching to create a more meaningful and activating learning environment. The major aim of this study was to compare possible effects of gamification on a traditional interactive teaching concept in a biochemistry course on ...
Eva Stapfer   +3 more
wiley   +1 more source

Environmental Disclosure Under Mandatory Regulation in EU Listed Companies: An Institutional Analysis

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study examines corporate environmental reporting practices among listed companies in the European Union during the period 2018–2022, within the context of the Non‐Financial Reporting Directive (NFRD). To this end, an Environmental Disclosure Index (EDI) is constructed based on qualitative reporting items, and panel‐data models are ...
Rosalva Pinto‐Braga   +2 more
wiley   +1 more source

Green Hydrogen for Public Transportation: Insights From an ABM and From Palma de Mallorca Case Study

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The development of green hydrogen (GH2) value chains is crucial for decarbonizing sectors such as transport and industry. Their emergence, however, requires coordination among diverse actors, technologies, and regulations, which traditional analytical approaches struggle to capture.
Roberta De Cristofaro   +2 more
wiley   +1 more source

Kolmogorov Complexity—A Primer

open access: yes, 2012
The Complexity of Things Previously on this blog (quite a while ago), we’ve investigated some simple ideas of using randomness in artistic design (psychedelic art, and earlier randomized css designs). Here we intend to give a more thorough and rigorous introduction to the study of the complexity of strings.
openaire   +1 more source

Predicting Coronary Occlusion Risk during Redo‐TAVR at First TAVR: Asymmetric Calcification Causes Failure

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background and Aims Predicting coronary artery occlusion due to sinus sequestration (SS) during a second transcatheter aortic valve (TAV) procedure using pre‐procedural computed tomography (CT) after the first TAV replacement (TAVR) is underreported.
Kyohei Onishi   +12 more
wiley   +1 more source

Long‐Term Impact of Prosthesis‐Patient Mismatch After Transcatheter Aortic Valve Replacement in Patients With Small Aortic Annuli

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Prosthesis‐patient mismatch (PPM) remains common following transcatheter aortic valve replacement (TAVR) and is associated with worse clinical outcomes. PPM is of particular concern in small aortic annuli (SAA). Aims To compare the incidence, predictors, and long‐term impact of PPM in SAA TAVR.
Itamar Loewenstein   +9 more
wiley   +1 more source

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