Results 131 to 140 of about 2,783,234 (200)

Trophoblast Extracellular Vesicles Rewire Immunity: A Symptom‐Relief Avenue for Recessive Dystrophic Epidermolysis Bullosa

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
First‐trimester trophoblast EVs are enriched in anti‐inflammatory proteins, lipids, and immunoregulatory miRNAs. EVT‐EVs reprogram monocytes toward a pro‐resolving phenotype and restore immune homeostasis in RDEB, supporting their potential as offering a scalable off‐the‐shelf therapy for chronic inflammatory diseases.
Nell Hirt   +8 more
wiley   +1 more source

1H HR‐MAS NMR Metabolomics in Combination With Transcriptomic Correlation Provides New Insights Into Metabolic Heterogeneity Across Breast Cancer Immunohistochemical Subtypes

open access: yesNMR in Biomedicine, Volume 39, Issue 10, October 2026.
Metabolomic profiling of breast cancer tissue using 1H HR‐MAS NMR spectroscopy and LCModel‐based quantitative analysis revealed metabolite differences associated with immunohistochemical subtypes, and subsequent metabolomics–transcriptomics integration linked these subtype‐dependent metabolic signatures to pathways in choline metabolism, one‐carbon ...
Irene Garcia‐Bocanegra   +10 more
wiley   +1 more source

Conserved Asp233–Asp246 hydrogen bond modulates active site dynamics in class A β‐lactamases

open access: yesProtein Science, Volume 35, Issue 10, October 2026.
Abstract Rigid enzymes catalyze chemical reactions by stabilizing the transition state through a specific conformation. Catalytic residues are precisely positioned, and enzyme dynamics are kept to a minimum. It is thought that conserved residues around the active site (second‐shell residues) play a crucial role in positioning catalytic residues. Asp233
Cristina V. Lopez‐Gallego   +3 more
wiley   +1 more source

Hydrogen Storage in Crystalline and Amorphous High‐Entropy Alloys: Linking Absorption/Desorption Kinetics to Structural–Morphological–Compositional Evolution

open access: yesRare Metals, Volume 45, Issue 10, October 2026.
ABSTRACT This study examines the hydrogen storage behavior in amorphous high‐entropy alloys (HEA), aiming to address the limited understanding of poorly crystalline systems compared to their crystalline counterparts, with emphasis on absorption/desorption kinetics and structural, morphological, and compositional evolution during hydrogenation ...
Ruiran Guo   +9 more
wiley   +1 more source

Operator-level quantum acceleration of non-logconcave sampling. [PDF]

open access: yesProc Natl Acad Sci U S A
Leng J, Ding Z, Chen Z, Lin L.
europepmc   +1 more source

A Semi‐Resolved LES‐DEM Framework for Turbulent Bedload Transport From Saltation to Sheet‐Flow Regimes

open access: yesWater Resources Research, Volume 62, Issue 10, October 2026.
Abstract Bedload transport widely occurs in natural environments and encompasses flow regimes from saltation to sheet‐flow, with markedly different fluid‐particle interaction characteristics. Understanding these mechanisms requires a numerical tool capable of capturing both the turbulence and fluid‐particle interactions, for which challenges exist due ...
Yuxiang Liu, Lu Jing, Zi Wu, Xudong Fu
wiley   +1 more source

The HydroGym reinforcement learning platform for fluid dynamics. [PDF]

open access: yesNature
Lagemann C   +20 more
europepmc   +1 more source

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