Results 31 to 40 of about 851,642 (267)

First reliable record of Liparis punctulatus (Scorpaeniformes: Liparidae) in Korea

open access: yesFisheries and Aquatic Sciences, 2021
A single specimen of Liparis punctulatus (30.9 mm standard length) belonging to the family Liparidae, was collected in the waters off Busan on 4 August, 2016.
Gyeong Hyun Park, Jin-Koo Kim
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Current Status of Hepatitis E Virus Infection in Korea

open access: yesGut and Liver, 2011
Hepatitis E virus (HEV) is an emerging pathogen associated with acute viral hepatitis, and HEV is becoming increasingly recognized. Approximately 2% of acute viral hepatitis is caused by HEV, and 18 cases of hepatitis E have been reported in Korea.
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

From Deterrence to Cooperative Security on the Korean Peninsula

open access: yesJournal for Peace and Nuclear Disarmament, 2020
The 2018 US-DPRK Singapore Summit introduced a new model to guide resolution of long-standing disputes on the Korean Peninsula: a “lasting and stable peace regime” could be created simultaneously with the “complete denuclearization of the Korean ...
Toby Dalton
doaj   +1 more source

A large outbreak of serovar Thompson infections associated with chocolate cake in Busan, Korea [PDF]

open access: yesEpidemiology and Health, 2019
OBJECTIVES This study aimed to reveal the epidemiologic characteristics of the outbreak of gastroenteritis caused by Salmonella enterica serovar Thompson in Busan Metropolitan City and to identify points for improvement to prevent of food-borne disease ...
Youngduck Eun   +10 more
doaj   +1 more source

The Role of Training Institutions and Academic Societies for the Training and Education of GI Fellows

open access: yesThe Korean Journal of Gastroenterology, 2021
The training and education of GI fellows are crucial issues for the training institutions and academic societies. Current circumstances about GI fellows are changing rapidly according to shortage of training period of the internal medicine residency ...
Jeong Hoon Lee
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

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