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Comparative Efficacy of Elinzanetant Versus Other Non‐Hormonal Pharmaceutical Therapies for the Treatment of Moderate‐to‐Severe Vasomotor Symptoms Associated With Menopause: A Network Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Elinzanetant, a novel, dual neurokinin‐targeted therapy, has been approved in various geographies for the treatment of moderate‐to‐severe vasomotor symptoms (VMS) associated with menopause. Objective To compare the efficacy of elinzanetant with non‐hormonal pharmaceutical treatments (nHT) in alleviating VMS.
Piotr Wojciechowski +8 more
wiley +1 more source

The Challenges of Informed Consent in High-Stakes, Randomized Oncology Trials: A Systematic Review

MDM Policy & Practice, 2019
Importance. Oncology trials often entail high-stakes interventions where potential for morbidity and fatal side effects, and for life-prolongation or cure, intensify bioethical issues surrounding informed consent.
Julia M. Nathe, Elizabeth F. Krakow
doaj +1 more source

Between Contingency and Necessity of Human Action. Are We Free in our Choices? [PDF]

, 2016
The point of departure of this paper is the characterization of human action as contingent or necessary (obligatory). The key question concerns the place for choice in the human action, i.e. are we free in our choices?
Żegleń, Urszula M.
core +1 more source

Proteomic and Transcriptomic Signatures of Poor Asthma Symptom Control in the U‐BIOPRED Cohort

Allergy, EarlyView.
No stable features were identified as associated with asthma symptom control in transcriptomics or sputum proteomics. Higher TWEAKR/TNFRSF12A and MBL/MBP‐C serum levels increased the odds of uncontrolled symptoms, while higher MK08/MAPK8 and CD5L serum levels decreased the odds, after adjustment for clinical variables.
Joana Antão +294 more
wiley +1 more source

The Role of Increased Sunshine in Shaping Air Temperature Rise in Kraków (1951–2020)

Quaestiones Geographicae
Since the late 1980s, air temperature in Kraków (southern Poland) has increased by ~2.2–2.3°C compared to the 1951–1988 average. Over the same period, a significant increase in sunshine duration (SD) (by about 500 hr) has been observed relative to the ...
Marsz Andrzej A., Matuszko Dorota, Styszyńska Anna +2 more
doaj +1 more source

Castlings in the margins: A change of perspective (Ewa Wróblewska-Trochimiuk, "Sztuka marginesów. Chorwacki plakat polityczny" ("The Art of Margins. The Croatian Political Poster"), Warszawa–Kraków: Instytut Slawistyki Polskiej Akademii Nauk – Libron, 2018, 324 pages)

Slavia Meridionalis, 2019
Castlings in the margins: A change of perspective (Ewa Wróblewska-Trochimiuk, Sztuka marginesów. Chorwacki plakat polityczny (The Art of Margins. The Croatian Political Poster), Warszawa–Kraków: Instytut Slawistyki Polskiej Akademii Nauk – Libron, 2018,
Lech A. Suchomłynow
doaj +1 more source

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

Allergy, EarlyView.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas +128 more
wiley +1 more source

The Life of Józef Warszewicz (1812–1866): the Kraków Period

Acta Baltica Historiae et Philosophiae Scientiarum, 2014
􀂑􀂐􀂇􀀃􀂑􀂈􀀃􀂖􀂊􀂇􀀃􀂏􀂑􀂕􀂖􀀃􀂒􀂔􀂑􀂎􀂋􀆤􀂅􀀃􀂐􀂋􀂐􀂇􀂖􀂇􀂇􀂐􀂖􀂊􀇦 􀂅􀂇􀂐􀂖􀂗􀂔􀂛􀀃􀂒􀂎􀂃􀂐􀂖􀀃􀂅􀂑􀂎􀂎􀂇􀂅􀂖􀂑􀂔􀂕􀀃􀂃􀂐􀂆􀀃􀂑􀂐􀂇􀀃􀂑􀂈􀀃􀂖􀂊􀂇􀀃􀂖􀂑􀂒􀀃􀆤􀂇􀂎􀂆􀀃􀂇􀂚􀂒􀂇􀂔􀂖􀂕􀀃􀂑􀂐􀀃􀂖􀂔􀂑􀂒􀂋􀂅􀂃􀂎􀀃􀀄􀂏􀂇􀂔􀂋􀂅􀂃􀂐􀀃 plants of his time, after spending several years on expeditions to Central and South America, was to be employed as Inspector (the main ...
Piotr Köhler
doaj +1 more source

Korespondencja Krakowa z miastami Górnych Węgier w średniowieczu

Klio, 2012
The letters from Krakow councillors and aldermen must be searched for in the archives of other cities of Poland and in the foreign archives for the fact that the medieval correspondence addressed to the Krakow’s city authorities as well as the registers
Stanisław A. Sroka
doaj +1 more source

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria

Allergy, EarlyView.
ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
T. Zuberbier +221 more
wiley +1 more source

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