Results 91 to 100 of about 406 (260)
Annals of Neurology, EarlyView.Objective Plasma biomarkers of Alzheimer's disease (AD) pathology are frequently tested in specialized research settings, which limits the generalizability of findings. Using electronic health records and banked plasma, we evaluated plasma biomarkers—phosphorylated tau 217 (p‐tau217), β‐amyloid 1–42/1–40 (Aβ42/Aβ40) and p‐tau217/Aβ42—in a real‐world ...
Katheryn A.Q. Cousins +12 more
wiley +1 more source
International Journal of Research in Engineering and Technology, 2015 The proposed method provides one of the efficient management and operation of the distribution network through reconfiguration. Whenever an outage occurs in the distribution network, there may be partial or total block out of the system. In order to reduce interruptions to the consumers, proper switching of power lines is required and restoration of ...
openaire +1 more source
Annals of Neurology, EarlyView.Objective Traumatic brain injury (TBI) is an established risk factor for dementia, although the underlying mechanisms remain unclear. Our previous research demonstrated that a single severe TBI in wild‐type (WT) mice induces a prion‐like form of tau (tauTBI) that spreads throughout the brain, leading to memory deficits.
Gloria Vegliante +19 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Whether cognitive decline in patients with Parkinson's disease (PD) carrying GBA1 variants is accelerated after subthalamic deep brain stimulation (STN‐DBS) remains controversial. Clarifying long‐term cognitive outcomes is essential for informed decision making.
Moritz A. Loeffler +8 more
wiley +1 more source
Trabecular bone ontogeny of the human talus
The Anatomical Record, EarlyView.Abstract Studies of trabecular ontogeny may provide insight into the factors that drive healthy bone development. There is a growing understanding of how the juvenile skeleton responds to these influences; however, gaps in our knowledge remain. This study aims to identify ontogenetic trabecular patterns and regional changes during development within ...
Rebecca A. G. Reid +2 more
wiley +1 more source
Serum Cytokine Profiling Differentiates Underlying Diseases in Cytokine Storm Syndrome
Arthritis &Rheumatology, EarlyView.Serum cytokine profiling was performed using Luminex (48 cytokines) and ELISA (5 cytokines). Assessment of key cytokines (IFN‐α, IL‐18, IL‐6, CXCL9) delineated five dominant inflammatory patterns: I, IFN‐α–dominant CSS; II, IL‐18–dominant CSS; III, IL‐6–dominant CSS; IV, IFN‐γ–dominant CSS; and V, IL‐6 & IFN‐γ intermediate CSS.
Shuya Kaneko +42 more
wiley +1 more source
Goodman and Kruskal's Gamma Coefficient for Ordinalized Bivariate Normal Distributions. [PDF]
Psychometrika, 2020 Barbiero A, Hitaj A.
europepmc +1 more source
Arthritis &Rheumatology, EarlyView.Objective Cellular mechanisms driving transition from psoriasis to psoriatic arthritis have remained largely elusive. Thus, we investigated changes within the peripheral blood T cell compartment associated with the transition phase. Methods In an observational study, 116 patients were examined and categorized into subgroups including psoriasis with at ...
Hanna Graßhoff +19 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin +15 more
wiley +1 more source