Results 31 to 40 of about 363,317 (191)

Oestrogen, an evolutionary conserved regulator of T cell differentiation and immune tolerance in jawed vertebrates? [PDF]

open access: yes, 2018
In teleosts, as in mammals, the immune system is tightly regulated by sexual steroid hormones, such as oestrogens. We investigated the effects of 17β-oestradiol on the expression of several genes related to T cell development and resulting T cell ...
Duflot, Aurélie   +5 more
core   +3 more sources

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Differential Effects of Increasing Salinity on Germination and Seedling Growth of Native and Exotic Invasive Cordgrasses [PDF]

open access: yes, 2019
Soil salinity is a key environmental factor influencing germination and seedling establishment in salt marshes. Global warming and sea level rise are changing estuarine salinity, and may modify the colonization ability of halophytes.
Castillo Segura, Jesús Manuel   +4 more
core   +2 more sources

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

MapReduce based big data framework using associative Kruskal poly Kernel classifier for diabetic disease prediction

open access: yesMethodsX
Recent trendy applications of Artificial Intelligence are Machine Learning (ML) algorithms, which have been extensively utilized for processes like pattern recognition, object classification, effective prediction of disease etc.
R. Ramani   +4 more
doaj   +1 more source

Pengaruh sistem zonasi sekolah terhadap pemanfaatan fasilitas pendukung di sekitar SMAN 1 dan SMAN 2 Surakarta

open access: yesRegion: Jurnal Pembangunan Wilayah dan Perencanaan Partisipatif, 2023
Sistem zonasi sekolah memiliki tujuan antara lain menghapuskan eksklusivitas dan diskriminasi antar sekolah serta mengurangi pergerakan siswa seiring mengecilnya jarak sekolah dengan tempat tinggal.
Mega Eka Maharani Agustiana   +2 more
doaj   +1 more source

Investigating the level of moral distress and its related factors among nurses in mazandaran burn center [PDF]

open access: yes, 2015
Background and purpose: Moral distress is a common phenomenon in nursing professional and burn nurses are constantly faced with making different moral decisions for patients who are in terrible conditions. Therefore, nurses in burn units experience moral
Aghaei, N.   +5 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Statistical analysis of the count and profitability of air conditioners

open access: yesData in Brief, 2018
This article presents the statistical analysis of the number and profitability of air conditioners in an Egyptian company. Checking the same distribution for each categorical variable has been made using Kruskal–Wallis test.
EL Houssainy A. Rady   +2 more
doaj   +1 more source

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