Results 241 to 250 of about 60,862 (368)

Recognition of Glycine Versus Nonglycine Citrulline Motifs Dictating the HLA Class II Association of Anticitrullinated Protein Antibodies: Insights From Autoantibody Profiling of 6,900 Scandinavian Patients With Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA)–associated anticitrullinated protein antibodies (ACPAs) target various antigens by binding short citrulline amino acid motifs, resulting in heterogeneous ACPA profiles among patients. Here we analyzed ACPA patterns by recognized citrulline motifs in relation to the RA risk factors HLA‐DRB1 shared epitope (SE) alleles
Linda Mathsson Alm   +18 more
wiley   +1 more source

Crystallographic insights into lipid-membrane protein interactions in microbial rhodopsins. [PDF]

open access: yesFront Mol Biosci
Bukhdruker S   +4 more
europepmc   +1 more source

The impact of traditional versus hotspot‐driven anatomy practical assessment on student cognitive processes

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Practical examinations are commonly implemented to assess student knowledge of human gross anatomy. The in‐person timed cadaveric practical is a classic assessment tool; however, several new approaches, like online or oral practical assessments, have become increasingly popular in recent years due to time, space, and/or financial constraints ...
Shanna Williams   +2 more
wiley   +1 more source

Trifluoroacetyl‐Substituted D–π–A Fluorophores: Design Strategies for Strong Solvatochromism and Giga Stokes Shifts

open access: yesChemistry – An Asian Journal, EarlyView.
Trifluoroacetyl‐substituted D–π–A fluorophore, featuring relatively extended and planar conjugated structure with piperidyl donor and trifluoroacetyl acceptor, demonstrated strong solvatochromism and giga Stokes shifts. This unique and strong acceptor has possibilities to achieve the design of fluorophore for various application, represented by ...
Alto Hori, Gen‐ichi Konishi
wiley   +1 more source

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

open access: yesBMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan   +12 more
wiley   +1 more source

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