Results 31 to 40 of about 7,550 (253)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Communications Biology, 2022 Noble gases are known to interact with proteins and can be good anaesthetics in hyperbaric conditions. This study identifies argon and krypton binding sites on membrane proteins and proposes as a hypothesis that noble gases, by altering protein/lipid ...
Igor Melnikov +17 more
doaj +1 more source
Optical Radiation during Sputtering of Lithium into a Noble Gas Using a Nanosecond Electron Beam
Applied Sciences, 2023 The optical radiation in a gaseous medium upon the irradiation of a lithium layer with a fast electron beam of a 5 ns duration has been studied. The irradiation chamber was filled with argon, krypton, or xenon at a pressure of 10 kPa up to 60 kPa.
Mendykhan Khasenov +5 more
doaj +1 more source
Advanced Engineering Materials, EarlyView.Coarse‐grained (left) and atomistic (right) models of the shape memory polymer ESTANE ETE 75DT3 are shown schematically. The two representations bridge molecular detail and mesoscopic description. Both models capture shape memory behavior, linking segmental mobility and conformational relaxation of anisotropic chains to macroscopic recovery, and ...
Fathollah Varnik
wiley +1 more source
Analytical measurements of fission products during a severe nuclear accident
EPJ Web of Conferences, 2018 The Fukushima accident emphasized the fact that ways to monitor in real time the evolution of a nuclear reactor during a severe accident remain to be developed.
Doizi D. +8 more
doaj +1 more source
Ultrafast quantum control of ionization dynamics [PDF]
EPJ Web of Conferences, 2019 The unprecedented combination of transient absorption and ion mass spectroscopy with attosecond resolution is used to study and control the complex multidimensional excitation and decay cascade of an ultrafast Auger process in krypton.
Hütten Konrad +13 more
doaj +1 more source
Advanced Engineering Materials, EarlyView.This study shows that superalloys used in aircraft engine disks become much more prone to deformation at high temperatures if they have been strained during manufacturing. This effect increases with the level of prior strain but eventually reaches a limit.
Fabio Machado Alves da Fonseca +9 more
wiley +1 more source
Advanced Functional Materials, EarlyView.We use scanning nitrogen vacancy magnetometry to directly image the weak in‐plane magnetic moments in mixed phase BiFeO3 at the nanoscale and quantify the local magnetic moments to be 18.8±2.0 μB/nm2 in the rhombohedral‐like phase and 1.5±0.6 μB/nm2 in the well‐known non‐magnetic tetragonal‐like phase.
Lei Wang +14 more
wiley +1 more source
Saturating multiple ionization in intense mid-infrared laser fields
New Journal of Physics, 2021 The interpretation of experimental data from novel mid-infrared few-cycle laser sources requires an understanding of ionization mechanisms and knowledge about related ion yields.
Franz E Haniel +14 more
doaj +1 more source