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Role of Kynurenine Pathway in Allergy
2015Tryptophan catabolism, including kynurenine pathway, is known to be involved in immunoregulation and its metabolites play a role in immune modulation. In the context of allergic diseases, it has been proposed that tryptophan degradation pathway, rather than tryptophan deprivation itself, plays an important role in tolerance induction during allergen ...
Shau Ku Huang, Hirokazu Kawasaki
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The Kynurenine Pathway and Neurologic Disease
1996Quinolinic acid (QUIN) is a neurotoxic metabolite of the tryptophan — kynurenine pathway (Bender, 1982) that selectively injures and kills vulnerable neurons via activation of the N-methyl-D-aspartate class of excitatory amino acid receptors (Stone, 1993).
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Kynurenine-An Old Pathway Retraced
Journal of Clinical Psychopharmacology, 2006openaire +3 more sources
Kynurenine pathway dysregulation in postpartum depression
Brain, Behavior, and Immunity, 2021openaire +3 more sources
Kynurenine pathway and cerebral ischemia
Pharmacological Research, 1995C. Speciale+7 more
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