This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang +15 more
wiley +1 more source
Alcohol abuse as a potential risk factor of solitary death among people living alone: a cross-sectional study in Kyoto, Japan. [PDF]
Miyamori D +6 more
europepmc +1 more source
NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang +18 more
wiley +1 more source
Pristionchus trametes n. sp. (Diplogastridae) isolated from the mushroom Trametes orientalis in Kyoto, Japan. [PDF]
Kanzaki N, Hamaguchi K.
europepmc +1 more source
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen +11 more
wiley +1 more source
Mona Makita,1,* Miyu Onishi,1,* Chika Kouno,1 Rika Kawabe,1 Naoki Doi,1 Yukinobu Tahu,2 Tomoki Aoyama,1 Momoko Nagai-Tanima1 1Department of Human Health Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan; 2Kyoto ...
Makita M +7 more
doaj
Analysis of a city-wide COVID-19 prevention strategy for aged-care facilities during third and fifth waves of COVID-19 in Kyoto City, Kyoto, Japan. [PDF]
Nagao M +7 more
europepmc +1 more source
Modern Masters of Kyoto: The Transformation of Japanese Painting Traditions—Nihonga from the Griffith and Patricia Way Collection. By Michiyo Morioka and Paul Berry. Seattle: Seattle Art Museum/University of Washington Press, 1999. 333 pp. $50.00. [PDF]
Ellen P. Conant
openalex +1 more source
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li +11 more
wiley +1 more source
Thortveitite from Kobe, Omiya, Kyoto, Japan [PDF]
Kin-ichi Sakurai +2 more
openaire +1 more source

