Results 51 to 60 of about 1,880,497 (367)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Whole-body and segmental muscle volume are associated with ball velocity in high school baseball pitchers

Open Access Journal of Sports Medicine, 2013
Yosuke Yamada,1,2 Daichi Yamashita,2,3 Shinji Yamamoto,2,3 Tomoyuki Matsui,4 Kazuya Seo,4 Yoshikazu Azuma,4 Yoshikazu Kida,5 Toru Morihara,5 Misaka Kimura1 1Laboratory of Sports and Health Science, Kyoto Prefectural University of Medicine, Kyoto, Japan ...
Yamada Y, Yamashita D, Yamamoto S, Matsui T, Seo K, Azuma Y, Kida Y, Morihara T, Kimura M   +8 more
doaj  

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Effectiveness of parent training in improving stress-coping capability, anxiety, and depression in mothers raising children with autism spectrum disorder

Neuropsychiatric Disease and Treatment, 2018
Naoko Iida,1,2 Yoshihisa Wada,1,3 Tatsuhisa Yamashita,1,2,4 Michiko Aoyama,5,6 Kiyoshi Hirai,5,6 Jin Narumoto1 1Department of Psychiatry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan; 2Department of Child ...
Iida N, Wada Y, Yamashita T, Aoyama M, Hirai K, Narumoto J   +5 more
doaj  

On Multibrane Solutions in Open String Field Theory

, 2011
Existence of open string field theory solutions describing configurations of multiple space-filling D-branes has been a subject of numerous speculations for quite some time.
Murata, Masaki, Schnabl, Martin
core   +1 more source

External impacts on traditional commons and present-day changes: a case study of iriai forests in Yamaguni district, Kyoto, Japan

, 2014
Japanese iriai forests have been regarded as a model of institutions for collective action in the sustainable use of resources in studies on commons, as pointed out by Ostrom (1990) and McKean (1996). However, present-day iriai forests that have survived
D. Shimada
semanticscholar   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Analytical study on street smoking ban by local ordinances in Japan, 2002-2018

Tobacco Induced Diseases, 2019
Objective Since 2002, street smoking ban has been enforced by local ordinances in municipalities in Japan. We analyzed the trends and development of these ordinances came into force from 2002 to 2018.
Suketaka Iwanaga, Kazunari Satomura, Mai Masuda, Toshitaka Nakahara   +3 more
doaj   +1 more source

Dipole and Bloch oscillations of cold atoms in a parabolic lattice

, 2005
The paper studies the dynamics of a Bose-Einstein condensate loaded into a 1D parabolic optical lattice, and excited by a sudden shift of the lattice center. Depending on the magnitude of the initial shift, the condensate undergoes either dipole or Bloch
A. J. Lichtenberg, A. R. Kolovsky, A. R. Kolovsky, A. V. Ponomarev, C. Zener, F. Nesi, F. S. Cataliotti, M. Ben Dahan, M. L. Chiofalo, M. Modugno, S. K. Adhikari   +10 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source