Results 151 to 160 of about 334,489 (293)

Smartly Assembled near‐Micron RF‐Responsive Agents Bridge Transarterial Embolization and Immunothermal Potentiation

Advanced Science, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) remains a significant clinical challenge due to the limited efficacy of conventional treatments like surgery, radiofrequency ablation (RFA), and transarterial embolization (TAE). Here, we develop an innovative TAE and immunothermal therapy strategy based on smartly assembled near‐micron layered double hydroxide ...
Qitao Hu, Junkang Ding, Lingxiao Zhang, Zhou Tian, Cheng Zeng, Shaomin Zou, Wenjing Zhang, Tangye Zeng, Zhencang Gao, Zhouyi Sun, Gang Liu, Weiyu Chen, Zhe Tang   +12 more
wiley   +1 more source

Temporal Patterns of Skin-Fixed Depth Electrodes During Stereotactic Electroencephalography Recording. [PDF]

Cureus
Kikuchi T, Sawada M, Demura A, Yamao Y, Yamada D, Yoshida T, Kobayashi K, Ikeda A, Matsumoto R, Arakawa Y.   +9 more
europepmc   +1 more source

Liver Kinase B1 in CD11c+ Cells Inhibits Fibrosis in Chronic Pancreatitis via the Oncostatin M Signaling

Advanced Science, EarlyView.
This study demonstrates significantly reduced Lkb1 expression in CD11c+ cells in chronic pancreatitis (CP) patients and animal models. Lkb1 deletion enhances CD11c+CD206+ macrophage infiltration and reprograms pancreatic stellate cells (PSCs) via OSM signaling.
Wenqing Zhang, Shan Guo, Yu Zhang, He Ren, Ke Lei, Chenyang Zhao, Qian Yu, Hongqing Luo, Yujing Xiao, Xiaoming Feng, Xiaoyu Li   +10 more
wiley   +1 more source

Correction to: Policy recommendations for promoting nuclear medicine therapy in Japan 2025, from the Working Group for promoting nuclear medicine therapy of the Japan Society of Clinical Oncology. [PDF]

Int J Clin Oncol
Suzuki K, Miyake H, Inaki A, Takano S, Kuboki Y, Mizowaki T, Nakamura K, Ueno M, Matsumoto S, Obinata D, Nakagawa T, Murakami M, Majima Y, Yokono M, Namba M, Yoshino T.   +15 more
europepmc   +1 more source

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li, Yajin Liao, Yan‐bo Zhao, Hongxing Wu, Tong Jin, Shuoshuo Li, Yuhan Liu, Peng Li, Songying Ouyang, Zekai Li, YuTing Xia, Qian Hua, Rui‐Yuan Pan, Zengqiang Yuan   +13 more
wiley   +1 more source

Increased Insulin Requirements in Severe Cases of Covid-19 are Higher Than in Moderate Cases

Diabetes, Metabolic Syndrome and Obesity
Takaaki Matsui,1 Emi Ushigome,1 Masahide Hamaguchi,1 Kazuki Sudo,2 Nobuko Kitagawa,1 Yuriko Kondo,1 Yuka Hasegawa,1 Dan Imai,1 Tomohiro Hattori,1 Masahiro Yamazaki,1 Teiji Sawa,2 Michiaki Fukui1 1Department of Endocrinology and Metabolism, Graduate ...
Matsui T, Ushigome E, Hamaguchi M, Sudo K, Kitagawa N, Kondo Y, Hasegawa Y, Imai D, Hattori T, Yamazaki M, Sawa T, Fukui M   +11 more
doaj  

Platform trial of smartphone-based cognitive-behavioural therapy (CBT) for depressive symptoms among people with no or subthreshold depression: a protocol for the Best, Efficient and Affordable Training in Resilience in Constant Evolution (BEATRICE) platform trial. [PDF]

BMJ Open
Furukawa TA, Noma H, Kojima M, Tajika A, Toyomoto R, Sakata M, Luo Y, Inoue K, Horikoshi M, Akechi T, Kawakami N, Kondo N, Nakayama T, Fukuma S, Christensen H, Whitton A, Lutz W, Cuijpers P, Kessler RC, Wason J, Nahum-Shani I.   +20 more
europepmc   +1 more source

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source

Dual‐Mode Type I/II Photosensitization of a Stable Mesoporous Hydrogen‐Bonded Organic Framework for Antibacterial Therapy

Advanced Science, EarlyView.
A π‐conjugated donor–acceptor PDI monomer undergoes hydrogen‐bonded self‐assembly to form a robust mesoporous framework. The ordered molecular arrangement promotes efficient intersystem crossing and charge separation, leading to simultaneous Type I and Type II reactive oxygen species generation with a high singlet oxygen quantum yield.
Yi‐Lun Cheng, Hui Yuan, Yuhang Li, Zi‐Yu Wang, Rui Wang, Qi Yin, Xue‐Ning Ren, Miao Zheng, Yi Zeng, Tian‐Fu Liu, Zaisheng Ye   +10 more
wiley   +1 more source

Reductive-defect-suppressed titanium oxynitrides <i>via</i> Ca₃N₂-assisted topochemical nitridation. [PDF]

Chem Sci
Sasahara Y, Yoshii K, Kato D, Yamamoto I, Tsutsui Y, Morisato K, Takeuchi H, Tsumori T, Takatsu H, Horike S, Seki S, Maeda K, Kageyama H.   +12 more
europepmc   +1 more source