Results 41 to 50 of about 334,489 (293)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Whole-body and segmental muscle volume are associated with ball velocity in high school baseball pitchers

open access: yesOpen Access Journal of Sports Medicine, 2013
Yosuke Yamada,1,2 Daichi Yamashita,2,3 Shinji Yamamoto,2,3 Tomoyuki Matsui,4 Kazuya Seo,4 Yoshikazu Azuma,4 Yoshikazu Kida,5 Toru Morihara,5 Misaka Kimura1 1Laboratory of Sports and Health Science, Kyoto Prefectural University of Medicine, Kyoto, Japan ...
Yamada Y   +8 more
doaj  

Toward a Critical Non-Humanism in Postwar Japan

open access: yesAsian Studies
In this article, I argue that the infamous discussions around “overcoming modernity” that occurred in Japan in 1942 shared Michel Foucault’s conceptual conflation between humanism and modernism.
Jay Hetrick
doaj   +1 more source

Kant's Concept of Happiness: Within and Beyond Usefulness [PDF]

open access: yes, 2010
Proceedings of the 3rd International Symposium between the Institute of Education, University of London (UK), and the Graduate School of Education, Kyoto University (Japan) : 21-22 September 2009 Institute of Education, University of ...
Hirose, Yuzo
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Brain structural abnormalities in behavior therapy-resistant obsessive-compulsive disorder revealed by voxel-based morphometry

open access: yesNeuropsychiatric Disease and Treatment, 2014
Nobuhiko Hashimoto,1 Shutaro Nakaaki,2 Akiko Kawaguchi,1 Junko Sato,1 Harumasa Kasai,3 Takashi Nakamae,4 Jin Narumoto,4 Jun Miyata,5 Toshi A Furukawa,6,7 Masaru Mimura2 1Department of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University ...
Hashimoto N   +9 more
doaj  

Response Paper to Atsuko Tsuji's 'The Event, Writing and the Self: Walter Benjamin's Language Theory' [PDF]

open access: yes, 2010
Proceedings of the 3rd International Symposium between the Institute of Education, University of London (UK), and the Graduate School of Education, Kyoto University (Japan) : 21-22 September 2009 Institute of Education, University of ...
Anna Kouppanou
core  

Fake Instability in the Euclidean Formalism [PDF]

open access: yes, 1996
We study the path-integral formalism in the imaginary-time to show its validity in a case with a metastable ground state. The well-known method based on the bounce solution leads to the imaginary part of the energy even for a state that is only ...
Aoyama, Hideaki   +4 more
core   +2 more sources

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Association Between Empirical Anti-Pseudomonal Antibiotics for Recurrent Lower Respiratory Tract Infections and Mortality: A Retrospective Cohort Study

open access: yesInternational Journal of COPD, 2022
Akihiro Shiroshita,1– 3 Shungo Yamamoto,4 Keisuke Anan,3,5 Hokuto Suzuki,1 Masafumi Takeshita,1 Yuki Kataoka3,6– 8 1Department of Respiratory Medicine, Ichinomiyanishi Hospital, Ichinomiya, Japan; 2Division of Epidemiology, Department of Medicine ...
Shiroshita A   +5 more
doaj  

Home - About - Disclaimer - Privacy