Results 101 to 110 of about 33,279 (211)

Living With Hypochondroplasia: A Qualitative Exploration of Children's and Caregivers' Experiences, Challenges, and Unmet Needs

open access: yesMolecular Genetics &Genomic Medicine, Volume 13, Issue 11, November 2025.
Summary of findings from a qualitative study on the experiences and unmet needs of children with hypochondroplasia and their caregivers. ABSTRACT Background Hypochondroplasia (HCH) is a rare genetic skeletal dysplasia characterized by short stature, disproportionate limbs, and complications such as learning differences.
Elisabeth M. Oehrlein   +8 more
wiley   +1 more source

Change of Pelvic Tilt before and after Gait in Patients with Lumbar Degenerative Kyphosis [PDF]

open access: bronze, 2009
Whoan-Jeang Kim   +8 more
openalex   +1 more source

Prematurely Aged Human Microglia Exhibit Impaired Stress Response and Defective Nucleocytoplasmic Shuttling of ALS Associated FUS

open access: yesAging Cell, Volume 24, Issue 11, November 2025.
We developed a human microglia aging model by doxycycline‐induced GFP‐progerin expression, which offers a valuable tool to study human microglial aging and its contribution to neurodegeneration. Induced HMC3‐Progerin cells exhibited increased age markers as well as transcriptomic alterations, including an age‐associated transcriptomic shift and ...
Christiane Hartmann   +16 more
wiley   +1 more source

Implementing an Optimized Perioperative Strategy for Percutaneous Vertebroplasty: Clinical Application and Outcome Evaluation

open access: yesOrthopaedic Surgery, Volume 17, Issue 11, Page 3178-3184, November 2025.
For patients with OVCF, performing PVP under the ERAS clinical pathway facilitates early pain relief, reduces the average LOS, shortens the postoperative first ambulation time, and significantly improves perioperative clinical outcomes. ABSTRACT Objective Percutaneous vertebroplasty (PVP) is a widely used minimally invasive procedure for the treatment ...
Zhiwu Zhang   +5 more
wiley   +1 more source

Functional kyphosis and lumbar kyphosis in adolescent paddlers

open access: yesRetos: Nuevas Tendencias en Educación Física, Deportes y Recreación, 2010
The objective of this study was to evaluate the frequency of functional kyphosis and lumbar kyphosis in adolescent paddlers. A total of 140 paddlers (mean age: 13,67 ± 0,61 years) participated in this study.
Pedro Ángel López-Miñarro   +1 more
doaj  

Intraoperative Neurophysiological Monitoring in Patients With Marfan Syndrome Scoliosis

open access: yesOrthopaedic Surgery, Volume 17, Issue 11, Page 3109-3115, November 2025.
This study assessed intraoperative neurophysiological monitoring (IONM) efficacy in patients with Marfan syndrome‐associated scoliosis during posterior spinal fusion, showing 89.8% SEP and 92.4% MEP success rates. MFS patients with larger Cobb angles of the main curve and larger DAR values at pre‐operation suffer a higher risk of failed IONM monitoring.
Kaiyi Cao   +6 more
wiley   +1 more source

Pediatric Scoliosis in Osteogenesis Imperfecta: From Genetic Mechanisms to Therapeutic Strategies

open access: yesOrthopaedic Surgery, Volume 17, Issue 11, Page 3036-3047, November 2025.
This review explores the genetic underpinnings and treatment strategies for spinal deformities in children with osteogenesis imperfecta. Emphasis is placed on emerging molecular insights and modern surgical techniques that improve the management of severe scoliosis and enhance patient outcomes.
Vladislav Muldiiarov   +2 more
wiley   +1 more source

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