Results 31 to 40 of about 36,641 (227)

Relationship between thoracic kyphosis and neural axis abnormalities in patients with adolescent idiopathic scoliosis

Journal of Children's Orthopaedics, 2018
Purpose Previous studies have suggested an association between increased thoracic kyphosis and neural axis abnormalities in patients with adolescent idiopathic scoliosis (AIS). However, the basis for this finding is unclear, and this association has been
I. Swarup, P. Derman, E. Sheha, J. Nguyen, J. Blanco, R. Widmann   +5 more
doaj   +1 more source

Back to the future in traumatic fracture shapes of lumbar spine: An analysis of risk of kyphosis after conservative treatment

Journal of Craniovertebral Junction and Spine, 2021
Introduction: Nonosteoporotic burst vertebral fracture could commonly be treated with conservative or surgical approach. Currently, decision-making process is based on thoracolumbar (TL) AO spine severity injury score.
Federico Fusini, Gabriele Colò, Salvatore Risitano, Alessandro Massè, Laura Rossi, Angela Coniglio, Massimo Girardo   +6 more
doaj   +1 more source

Progressive Spinal Kyphosis in the Aging Population.

, 2023
Thoracic kyphosis tends to increase with age. Hyperkyphosis is defined as excessive curvature of the thoracic spine and may be associated with adverse health effects.
Harrop, James S, Shaffrey, Christopher I, Lenke, Lawrence G, Smith, Justin S, Ailon, Tamir   +4 more
core   +1 more source

Maximum gait speed and lumbar spinal mobility can affect quality of life in elderly women with lumbar kyphosis

North American Spine Society Journal, 2022
Background: The site and angle of kyphosis are important factors that affect quality of life (QOL). Lumbar kyphosis, rather than thoracic kyphosis, is reported to affect the QOL in patients with kyphosis.
Tatsuya Endo, Osamu Shirado, Ryoji Tominaga, Keita Sato, Takuya Miura, Masumi Iwabuchi, Toshikazu Ito   +6 more
doaj   +1 more source

Long-term administration of antisense oligonucleotides into the paraspinal muscles of mdx mice reduces kyphosis

, 2008
The mdx mouse model of muscular dystrophy has a premature stop codon preventing production of dystrophin. This results in a progressive phenotype causing centronucleation of skeletal muscle fibers, muscle weakness and fibrosis and kyphosis.
Laws, Nicola, Fletcher, Susan, Cornford-Nairn, Renee A., Wilton, Stephen D., Hoey, Andrew J., Irwin, Nicole, Johnsen, Russell   +6 more
core   +1 more source

Congenital cervical kyphosis in two young sighthounds

, 2015
Introduction: Cervical vertebral (C) malformation is rarely reported in large breed dogs. Congenital cervical kyphosis (CCK) may result from defects of vertebral segmentation, failure of formation or both.
Howard, J., Karli, Philemon, Precht, Maria Christina, Casoni, Daniela, Tomek, Ales, Forterre, Franck   +5 more
core   +1 more source

Postoperative alterations of sagittal cervical alignment and risk factors for cervical kyphosis in 124 Lenke 1 adolescent idiopathic scoliosis patients

BMC Musculoskeletal Disorders, 2021
Background This study aims to analyze postoperative changes of cervical sagittal curvature and to identify independent risk factors for cervical kyphosis in Lenke type 1 adolescent idiopathic scoliosis (AIS) patients.
Junyu Li, Kaige Deng, Yanchao Tang, Zexi Yang, Xiaoguang Liu, Zhongjun Liu, Feng Wei, Fengliang Wu, Hua Zhou, Yan Li, Yongqiang Wang, Weishi Li, Miao Yu   +12 more
doaj   +1 more source

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

Advanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li, Xijia Wang, Yaning Hu, Zhen Yang, Tian Niu, Xingbo Zhao   +5 more
wiley   +1 more source

Defining Features of Gabriele‐de Vries Syndrome in Adults: A Case Report and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Gabriele‐de Vries syndrome (GADEVS) is a neurodevelopmental disorder caused by heterozygous pathogenic variants in the YY1 gene. Like most rare genetic syndromes, the adult manifestations of GADEVS remain poorly defined. Here, we describe the oldest patient reported to date with GADEVS—a 63‐year‐old woman with a c.1177_1179del YY1 variant ...
Ethan W. Hollingsworth, Changrui Xiao
wiley   +1 more source