Results 31 to 40 of about 101,946 (198)
Recent Development of High-Energy Short-Pulse Lasers with Cryogenically Cooled Yb:YAG
Applied Sciences, 2022 High-power solid-state lasers are among the hot research directions at the forefront of laser research and have major applications in industrial processing, laser-confined nuclear fusion, and high-energy particle sources. In this paper, the properties of
Yuan Sui +3 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Single-cavity dual-comb fiber lasers and their applications
Frontiers in Physics, 2023 Single-cavity, dual-comb lasers are those specially designed mode-locked lasers that can emit more than one, asynchronous ultrashort pulse trains with stable repetition frequency difference between them.
Jianjun Yang +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Fibre Lasers: Promising Solutions
PhotonicsThis work analyses promising solutions for controlling the output radiation properties of fibre lasers. The design of fibre lasers is radically different from that of other laser types.
Sergey Kobtsev
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Recent Advances in χ(2)‐Based Nonlinear Frequency Conversion of Fiber Lasers
Advanced Photonics ResearchLasers operating in the visible and 3–20 μm mid‐infrared (MIR) spectral ranges have become indispensable tools with broad and significant applications in fields such as display technology, biomedicine, laser‐guide‐star systems, and nonlinear optics.
Bing Han +10 more
doaj +1 more source