Results 41 to 50 of about 515 (161)
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.ABSTRACT Oral pre‐exposure prophylaxis (PrEP) can substantially reduce HIV infection risk when taken as prescribed. However, many individuals struggle adhering to the daily regimen. Twice‐yearly injections of the novel HIV capsid inhibitor lenacapavir (LEN) demonstrated potential in recent PrEP trials.
Hee‐yeong Kim +3 more
wiley +1 more source
Tách chiết, tinh sạch và xác định đặc tính sinh học của chất kháng nấm và chất kháng khuẩn từ chủng vi khuẩn Bacillus velezensis CP 1604 [PDF]
, 2016 Bacillus velezensis is one of the members of the Bacillus subtilis species complex which is generally considered as safety organism. The bacterium possesses several beneficial properties for crops, especially production of antifungal and antibacterial ...
Hợp, Dương Văn +4 more
core +2 more sources
Advanced Science, Volume 13, Issue 21, 13 April 2026.Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider +20 more
wiley +1 more source
Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.ABSTRACT Adeno‐associated virus (AAV) gene therapies have achieved some clinical success, with multiple products reaching regulatory approval. Encapsulation of AAV vectors within engineered extracellular vesicles (EVs) is an emerging strategy which could help overcome challenges including pre‐existing anti‐capsid immunity and the need for controlling ...
Jonathan D. Boucher +5 more
wiley +1 more source
Journal of Applied Crystallography, Volume 59, Issue 2, Page 303-315, April 2026.A user‐friendly fixed‐target platform for serial synchrotron crystallography is described, which allows low‐background X‐ray diffraction data collection, in situ crystallization and transportation of protein microcrystals at room temperature.Fixed‐target platforms provide convenient support for microcrystals during serial X‐ray crystallography studies ...
Swagatha Ghosh +13 more
wiley +1 more source
Tạp chí Khoa học Đại học Cần Thơ, 2011 Nghiên cứu được thực hiện nhằm đánh giá hiệu quả lên men của dòng nấm men Saccharomyces đã được phân lập và tuyển chọn từ nước thốt nốt so với nấm men thương mại trong quá trình sản xuất rượu vang thốt nốt. ảnh hưởng của số lượng tế bào nấm men phân lập (
Nguyễn Minh Thủy +7 more
doaj
In vitro liquid shake culture technique for biomass production of a native medicinal orchid (Anoectochilus roxburghii (Wall.) Lindl. [PDF]
, 2019 This study presented the rapid multiplication system of Anoectochilus roxburghii (Wall.) Lindl. in vitro and the liquid shake culture technique for biomass production capable of being used as a source of pharmaceutical materials. Stem segments (1.5-2 cm
Mai Trường, Nguyễn Thanh Mai
core +2 more sources
Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.This study used sedimentary eDNA analysis and field‐based microcosms to assess the impacts of three major aquatic contaminants on bacterial assemblage structure. Our results showed significant but varied impact depending on exposure to which contaminant; we suggest five phyla, 13 families, and three species as potential bacterial bioindicators and ...
A. S. Flynn +4 more
wiley +1 more source
Aggregate, Volume 7, Issue 3, March 2026.A precise dual‐targeting covalent organic framework (COF) nanoplatform that avoids aggregation‐caused quenching (ACQ) to achieve synergistic high‐efficiency Type I photodynamic therapy and chemotherapy. ABSTRACT There is an urgent need to develop innovative therapeutic strategies for hepatocellular carcinoma (HCC) treatment with severe hypoxia ...
Xiang Wang +9 more
wiley +1 more source
Molecular Oncology, Volume 20, Issue 2, Page 369-388, February 2026.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source