Results 191 to 200 of about 551,623 (249)

Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen   +16 more
wiley   +1 more source

Behavior Decoding Delineates Seizure Microfeatures and Associated Sudden Death Risks in Mouse Models of Epilepsy

open access: yesAnnals of Neurology, EarlyView.
Objective Behavior and motor manifestations are distinctive yet often overlooked features of epileptic seizures. Seizures can result in transient disruptions in motor control, often organized into specific behavioral sequences that can inform seizure types, onset zones, and outcomes.
Yuyan Shen   +8 more
wiley   +1 more source

Molecular genetic characterization of <i>Cryptosporidium</i> and <i>Cystoisospora</i> protozoan infections in cats from large cities of Kazakhstan. [PDF]

open access: yesFront Parasitol
Lider L   +7 more
europepmc   +1 more source

A Multiepitope‐Based Lateral Flow Assay for Leprosy Antibodies

open access: yesAnalysis &Sensing, EarlyView.
An innovative lateral flow assay for leprosy diagnosis is based on gold nanoparticles and synthetic Mycobacterium leprae epitopes conjugated to keyhole limpet hemocyanin protein to enhance antibody detection. This strategy provides a rapid, accurate, and low‐cost approach for resource‐limited settings, enabling the early detection of infection. Leprosy
Cristiane Zocatelli‐Ribeiro   +7 more
wiley   +1 more source

Commissioning an Inexpensive Off‐The‐Shelf Spectrograph for Radial‐Velocity Studies

open access: yesAstronomische Nachrichten, EarlyView.
ABSTRACT We present a way to set up an inexpensive out of the shelf spectrograph at a local observatory. Stability and resolution of the spectrograph are high enough for radial velocity determination of binary stars or determination of stellar characteristics. Even some exoplanets might be detectable via the radial velocity method.
Lukas Stock, Andreas Schrimpf
wiley   +1 more source

Scaling of Planar Sodium‐Nickel Chloride Battery Cells to 90 cm2 Active Area

open access: yesBatteries &Supercaps, Volume 8, Issue 3, March 2025.
Large planar Na β′′ alumina electrolytes are prepared by tape‐casting and die‐pressing. These ceramic electrolytes are used to prepare planar sodium‐nickel chloride cells with 90 cm2 active area, providing a high capacity of 7 Ah. Successful cell cycling is demonstrated at 300 °C at rates up to C/4 (20 mA cm−2) for a cumulative capacity of 3.6 Ah cm−2.
T. Lan   +10 more
wiley   +1 more source

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