Results 161 to 170 of about 280,475 (248)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Primary Mitochondrial-Disorders-Associated Nephropathy in Adulthood. [PDF]

Kidney Int Rep
Bakis H, Trimouille A, Schwarz M, Combe C, Boudhabhay I, Martin-Négrier ML, Rigothier C.   +6 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Case Report: Postoperative pulmonary embolism causing obstructive shock and circulatory collapse after gynecologic surgery: successful rescue with VA-ECMO. [PDF]

Front Cardiovasc Med
Long NK, Dai HQ, Anh CHT, Dat PD, Tuan KM, Nhat TH, Tin NH, Tuan VPA, Nhut NM, Hai NT, Thuong DT.   +10 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Review of Inorganic Separator Engineering for Next-Generation Lithium-Sulfur Batteries: Compromise or Cornerstone? [PDF]

Adv Mater
Qin Y, Wang T, Wang X, Xu K, Wang Y, Wang C, Sun B, Wang G.   +7 more
europepmc   +1 more source

Nâng cao sự hài lòng của khách hàng qua đánh giá trực tuyến ở khách sạn Thành Tài : Đề án Thạc sĩ Du lịch [Mã số : 8810101]

90 tr.Phân tích và đánh giá các đánh giá của khách hàng trên Agoda: Nghiên cứu sẽ tiến hành phân tích và đánh giá các đánh giá từ khách hàng trên Agoda để xác định thông tin quý giá về ý kiến, nhận xét và kinh nghiệm của khách hàng với dịch vụ khách sạn.
Nguyễn, Nhật Trường
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Combined Bioinformatic Analysis and RNA Sequencing Uncover Key Tinnitus-Related Molecules in the Cingulate Gyrus. [PDF]

Int J Mol Sci
Jin Y, Shi X, Zhang Q, Guo B, Xiong Y, Hu Y, He H, Gao P, Chen W.   +8 more
europepmc   +1 more source