Results 91 to 100 of about 4,143,183 (252)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Non-linear dependence of ion heat flux on plasma density at the L–H transition of JET NBI-heated deuterium–tritium plasmas

open access: yesNuclear Fusion
Recent JET D–T campaigns opened the possibility of unique isotope studies to investigate the L–H transition physics in view of reactor plasmas and to study the origin of the observed power threshold minimum.
P. Vincenzi   +9 more
doaj   +1 more source

SUSY and the Electroweak Phase Transition

open access: yes, 1996
We analyze the effective 3 dimensional theory previously constructed for the MSSM and multi-Higgs models to determine the regions of parameter space in which the electroweak phase transition is sufficiently strong for a $B+L$ asymmetry to survive in the ...
Abe   +21 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Gravitational waves from phase transition in a supersymmetric left-right model

open access: yesJournal of High Energy Physics
We investigate the cosmological phase transition dynamics in a supersymmetric left-right symmetric model based on the gauge group SU(3) C × SU(2) L × SU(2) R × U(1) B−L that addresses the strong CP problem through extended parity symmetry and doublet ...
Naoyuki Haba   +2 more
doaj   +1 more source

Spatiotemporal and Wavenumber Resolved Bicoherence at the Low to High Confinement Transition in the TJ-II Stellarator

open access: yes, 2013
Plasma turbulence is studied using Doppler reflectometry at the TJ-II stellarator. By scanning the tilt angle of the probing beam, different values of the perpendicular wave numbers are probed at the reflection layer. In this way, the interaction between
Ascasíbar, E.   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

D-shaped configurations in FTU for testing liquid lithium limiter: Preliminary studies and experiments

open access: yesNuclear Materials and Energy, 2017
The feasibility of getting “D” shaped plasma configurations in FTU, with a possible X point close to the first wall, has been investigated with the aim of achieving an H-mode regime in this machine.
G. Ramogida   +33 more
doaj   +1 more source

Study of the second magnetization peak and the pinning behaviour in Ba(Fe$_{0.935}$Co$_{0.065}$)$_2$As$_2

open access: yes, 2017
Isothermal magnetic field dependence of magnetization and the magnetic relaxation measurements were performed for $H$$\parallel$c axis on single crystal of Ba(Fe$_{0.935}$Co$_{0.065}$)$_2$As$_2$ pnictide superconductor having $T_c$ = 21.7 K.
Alvarenga, A. D.   +5 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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