Results 81 to 90 of about 4,318,133 (264)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Heating neutral beams for ITER: negative ion sources to tune fusion plasmas

open access: yesNew Journal of Physics, 2017
Neutral beam injection (NBI) based on a negative ion source is one of the basic heating and current drive systems designed for ITER required to reach its goals of the operation with high fusion power, P _fus  ∼ 500 MW with fusion gain, Q  = 10 for 400 s ...
M J Singh   +4 more
doaj   +1 more source

D-shaped configurations in FTU for testing liquid lithium limiter: Preliminary studies and experiments

open access: yesNuclear Materials and Energy, 2017
The feasibility of getting “D” shaped plasma configurations in FTU, with a possible X point close to the first wall, has been investigated with the aim of achieving an H-mode regime in this machine.
G. Ramogida   +33 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Recent progress towards a physics-based understanding of the H-mode transition

open access: yes, 2016
Results from recent experiment and numerical simulation point towards a picture of the L-H transition in which edge shear flows interacting with edge turbulence create the conditions needed to produce a non-zero turbulent Reynolds stress at and just ...
G. Tynan   +7 more
semanticscholar   +1 more source

Concurrent Treatment With Lorlatinib and Dinutuximab Beta Induced Acute Gastric Dilation in a Pediatric Patient With Neuroblastoma

open access: yes
Pediatric Blood &Cancer, EarlyView.
Suna Lin   +6 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Effects of Different Extraction Methods on the Composition and Properties of Jinggang Pomelo Peel Essential Oil

open access: yesShipin gongye ke-ji
Taking Jinggang pomelo peel essential oil (JPPEO) as the research object, two methods of steam distillation and low-temperature continuous phase transition were used for extraction. Orthogonal test was used to study the effects of extraction temperature,
Xin LI   +5 more
doaj   +1 more source

Synthesis, Characterisation and Antimicrobial Evaluation of a New Bis(semicarbazone) Ligand and Its Coordination Complexes [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة
This study aimed to synthesise a new multidentate bis(semicarbazone) ligand, (2Z,2'E)-2,2'-(((propane-1,3-diylbis(oxy))bis(2,1-phenylene))bis(methanylylidene))-bis(hydrazine-1-carboxamide) (H₂L), and to investigate its paramagnetic coordination compounds
Mohamad Hameed, Mohamad Al-Jeboori
doaj   +1 more source

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