Results 61 to 70 of about 723,696 (218)
The feasibility of getting “D” shaped plasma configurations in FTU, with a possible X point close to the first wall, has been investigated with the aim of achieving an H-mode regime in this machine.
G. Ramogida +33 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Taking Jinggang pomelo peel essential oil (JPPEO) as the research object, two methods of steam distillation and low-temperature continuous phase transition were used for extraction. Orthogonal test was used to study the effects of extraction temperature,
Xin LI +5 more
doaj +1 more source
Synthesis, Characterisation and Antimicrobial Evaluation of a New Bis(semicarbazone) Ligand and Its Coordination Complexes [PDF]
This study aimed to synthesise a new multidentate bis(semicarbazone) ligand, (2Z,2'E)-2,2'-(((propane-1,3-diylbis(oxy))bis(2,1-phenylene))bis(methanylylidene))-bis(hydrazine-1-carboxamide) (H₂L), and to investigate its paramagnetic coordination compounds
Mohamad Hameed, Mohamad Al-Jeboori
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Dimorphism of Trichosporon cutaneum and impact on its lipid production
Background Compared to the oleaginous yeast Yarrowia lipolytica, Trichosporon cutaneum can metabolize pentose sugars more efficiently, and in the meantime is more tolerant to inhibitors, which is suitable for lipid production from lignocellulosic biomass.
Ya Wang +5 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The separatrix operational space (SepOS) model (Eich and Manz 2021 Nucl. Fusion 61 086017) is shown to predict the L–H transition, the L-mode density limit, and the ideal magnetohydrodynamic ballooning limit in terms of separatrix parameters for a wide ...
M.A. Miller +15 more
doaj +1 more source

