Results 151 to 160 of about 4,318,133 (264)

Cryogenic magnetocaloric effect in a disordered double-perovskite Gd₂MnZnO₆. [PDF]

RSC Adv
Petrov DN, Ćwik J, Koshkid'ko YS, Babij M, Ho TA, Phan TL, Khan DT, Dang NT, My KTH, Kim DH.   +9 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Discovery of functional compounds from dimorphic edible <i>Ophiocordyceps sinensis</i> fungus in host haemolymph. [PDF]

Synth Syst Biotechnol
Sun T, Yang Y, Xie J, Rao Z, Han R, Cao L.   +5 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Four ppm measurement of the antihydrogen ground-state hyperfine splitting. [PDF]

Nature
Akbari R, de Araujo Azevedo LO, Baker CJ, Bertsche W, Bhatt NM, Bonomi G, Capra A, Carli I, L Cesar C, Charlton M, Cridland Mathad A, Del Vincio A, Duque Quiceno D, Eriksson S, Evans A, Fajans J, Friesen T, Fujiwara MC, Golino LM, Gomes Gonçalves MB, Hangst JS, Hayden ME, Heidari P, Hodgkinson D, Isaac CA, Jones SA, Jonsell S, Madsen N, Marshall VR, McKenna JTK, Momose T, Nauta J, Oliveira AN, Powell A, Rasmussen CØ, Robertson-Brown T, Robicheaux F, Sacramento RL, Sarid E, Schoonwater J, Silveira DM, Singh J, Smith G, So C, Stracka S, Suh J, Swadling AG, Tharp TD, Thompson KA, Thompson RI, Thorpe-Woods E, Uribe Jimenez AJ, Urioni M, van de Werf DP, Wilson SG, Woosaree P, Wurtele JS, ALPHA Collaboration.   +57 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Hesperidin Inhibits Proliferation and Metastasis of Human Breast Cancer Cells by Suppressing MMP-2/9 Activity and Reversing Epithelial-Mesenchymal Transition. [PDF]

Cancer Inform
Hu H, Zhang C, Liu Z.
europepmc   +1 more source

L to H mode transition: on the role of Zeff

, 2013
C. Bourdelle, C. Maggi, L. Chôné, P. Beyer, J. Citrin, N. Fedorczak, X. Garbet, A. Loarte, F. Millitello, M. Romanelli, Y. Sarazin, J. Contributors   +11 more
semanticscholar   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Transition metal-induced excess electron localization driving the giant first hyperpolarizability in alkaline earthides: a DFT and TD-DFT study. [PDF]

RSC Adv
Hussain J, Hussain R, Tahreem D, Ahsan A, Arshad M, Ayub K.   +5 more
europepmc   +1 more source