Results 51 to 60 of about 983,702 (265)

Shearless edge transport barriers in L-H transition

open access: yes, 2022
9 pages and 6 figuresThe L-H transition leads to a substantial reduction in transport levels in tokamaks and stellarators, improving the plasma confinement in such devices. After the transition, the plasma is in a high-confinement regime characterized by
Caldas, I. L.   +13 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Influence of n = 1 resonant magnetic perturbation on flow and turbulence towards L-H transition

open access: yesNuclear Fusion
The application of resonant magnetic perturbation (RMP) with toroidal mode number n  = 1 on HL-3 tokamak inhibits the L-H transition at specific heating power.
Y. Zhang   +16 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

L-H transition studies on spherical tokamaks [PDF]

open access: yes, 2023
While the higher fusion power achieved in high confinement (H-)mode make it a desirable regime for tokamak devices, the transition from low confinement (L-)mode to H-mode is a complex, multi-faceted process whose dynamics are still not fully understood ...
Howlett, Lena
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Dynamics of E-H mode transition in high-pressure RF inductively coupled plasmas [PDF]

open access: yes, 2005
Capacitive (E) to inductive (H) mode transition dynamics in radio frequency (RF) argon inductively coupled plasmas (ICPs) with up to atmospheric pressure is studied experimentally. High-speed imaging (13500 fps) is performed to investigate the transition
Takamura, Shuichi   +2 more
core   +1 more source

Phase transition temperatures of 405-725 K in superfluid ultra-dense hydrogen clusters on metal surfaces

open access: yesAIP Advances, 2016
Ultra-dense hydrogen H(0) with its typical H-H bond distance of 2.3 pm is superfluid at room temperature as expected for quantum fluids. It also shows a Meissner effect at room temperature, which indicates that a transition point to a non-superfluid ...
Leif Holmlid, Bernhard Kotzias
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Reduced model for H-mode sustainment in unfavorable drift configuration in ASDEX Upgrade

open access: yesNuclear Fusion
A recently developed reduced model of H-mode sustainment based on interchange-drift-Alfvén turbulence description in the vicinity of the separatrix matching experimental observations in ASDEX Upgrade has been extended to experiments with the unfavorable $
O. Grover   +8 more
doaj   +1 more source

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