Results 101 to 110 of about 409 (115)
FEBS Letters, 2012 Low plasma homoarginine has emerged as a risk marker for cardiovascular disease. We exploited cells of a patient with a rare inborn error of metabolism to explore potential pathways of homoarginine synthesis, using stable isotopes and mass spectrometry ...
Mariska Davids +2 more
exaly +2 more sources
American Journal of Physiology - Heart and Circulatory Physiology, 2021 The creatine kinase system facilitates energy transfer between mitochondria and the major ATPases in the heart. Creatine-deficient mice, which lack arginine-glycine amidinotransferase (AGAT) to synthesize creatine and homoarginine, exhibit reduced ...
Martin Laasmaa +2 more
exaly +2 more sources
EpilepsiaAbstract We aim to determine whether epilepsy can be considered part of the arginine:glycine amidinotransferase (AGAT) deficiency syndrome phenotype and to identify its associated electroclinical signatures. We reviewed clinical data from our center, identifying individuals with AGAT deficiency. Each individual underwent a dedicated epilepsy assessment
Francesco Fortunato +2 more
exaly +2 more sources
Validation and Optimization of a Stable Isotope-Labeled Substrate Assay for Measuring AGAT Activity
International Journal of Molecular SciencesL-arginine: glycine amidinotransferase (AGAT) gained academic interest as the rate-limiting enzyme in creatine biosynthesis and its role in the regulation of creatine homeostasis.
Dahai Wang +2 more
exaly +3 more sources
Some of the next articles are maybe not open access.