Results 11 to 20 of about 12,607,381 (214)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
A construction grammar account of possessive constructions in Lancashire dialect : some advantages and challenges. [PDF]
, 2007 This study investigates reduction of 1SG possessives in possessive–noun constructions in Lancashire dialect. On the basis of a corpus of twenty-six interviews we show that reduction patterns according to (in)alienability.
Siewierska, Anna, Hollmann, Willem B.
core +2 more sources
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source
, 2020 This chapter charts the history of English grammar writing from the first published grammar of 1586 up to the end of the second decade of the 21st century. The first section covers the period up to the latter part of the 19th century, embracing grammars
Linn, A., Andrew R. Linn
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On Reconstructing Proto-Bantu Grammar
, 2022 This book is about reconstructing the grammar of Proto-Bantu, the ancestral language at the origin of current-day Bantu languages. While Bantu is a low-level branch of Niger-Congo, the world’s biggest phylum, it is still Africa’s biggest language family.
Bostoen, Koen de Schryver, Gilles-Maurice Guérois, Rozenn Pacchiarotti, Sara +3 more
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Arthritis Care &Research, EarlyView.Objective This study aimed to investigate hand function trajectories over five years in primary hand osteoarthritis (OA). Additionally, determinants of baseline and longitudinal hand function were assessed. Methods A total of 538 patients with both baseline and five‐year study visits were analyzed.
Annemiek V. E. M. Olde Meule +4 more
wiley +1 more source
Rutgers College Grammar School
, 1870 The Grammar School was chartered in 1766 as the Queen's College Grammar School. In 1825, Queen's College was renamed Rutgers College, and in 1883, the Grammar School was renamed the Rutgers Preparatory School. The Rutgers Preparatory School remained in
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