Results 231 to 240 of about 31,622 (258)

L-citrulline attenuates lipopolysaccharide-induced inflammatory lung injury in neonatal rats

Pediatric Research, 2023
Prenatal or postnatal lung inflammation and oxidative stress disrupt alveolo-vascular development leading to bronchopulmonary dysplasia (BPD) with and without pulmonary hypertension. L-citrulline (L-CIT), a nonessential amino acid, alleviates inflammatory and hyperoxic lung injury in preclinical models of BPD.
Nikola, Ivanovski, Huanhuan, Wang, Harvard, Tran, Julijana, Ivanovska, Jingyi, Pan, Emily, Miraglia, Sharon, Leung, Melanie, Posiewko, Daniel, Li, Atefeh, Mohammadi, Randa, Higazy, Anita, Nagy, Peter, Kim, Giles, Santyr, Jaques, Belik, Nades, Palaniyar, Estelle B, Gauda   +16 more
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Nitrites and L-citrulline levels in copper intrauterine device users

Contraception, 1997
The mechanism of copper in limiting intrauterine infections in intrauterine device (Cu IUD) users is poorly understood. Copper ions may enhance the release of reactive oxygen radicals, which in turn decrease the release of reactive nitrogen intermediates (RNI). RNI are known to have bactericidal effect.
M, Pradhan, I, Gupta, N K, Ganguli
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Determination of Urinary L-citrulline by Enzymatic Method

Chinese Journal of Analytical Chemistry, 2006
Abstract L -citrulline is an important marker in many diseases. A simple, accurate, and rapid enzymatic method is proposed for the determination of L -citrulline for its bioconversion by ornithine transcarbamoylase (OTC, EC 2.1.3.3) and carbamate kinase (CK, EC 2.7.2.2). The optimized conditions for the bioconversion were 30–35°C and pH 6–7.
Jiayou Li, Yu Cao, Qian Liu, Qingcai Jiao   +3 more
openaire   +1 more source

Monoclonal L‐Citrulline Immunostaining Reveals Nitric Oxide‐Producing Vestibular Neurons

Annals of the New York Academy of Sciences, 2001
Abstract: Nitric oxide is an unstable free radical that serves as a novel messenger molecule in the central nervous system (CNS). In order to understand the interplay between classic and novel chemical communication systems in vestibular pathways, the staining obtained using a monoclonal antibody directed against L‐citrulline was compared with the ...
G R, Holstein, V L, Friedrich, G P, Martinelli   +2 more
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Plasma l -citrulline concentrations in l -arginine–supplemented healthy dogs

Journal of Veterinary Cardiology, 2017
To determine whether oral l-arginine increases plasma [l-citrulline] in dogs.Eleven healthy staff-owned dogs were used in this study.Dogs (n = 3) were given l-arginine (50mg/kg PO q8h) for 7 days, and plasma [l-arginine] and [l-citrulline] were analyzed by high performance liquid chromatography at baseline (BL), steady state trough, and 0.5, 1, 1.5, 2,
K M, Flynn, H B, Kellihan, L A, Trepanier   +2 more
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L-Citrulline immunostaining identifies nitric oxide production sites within neurons

Neuroscience, 2002
The cellular and subcellular localization of L-citrulline was analyzed in the adult rat brain and compared with that of traditional markers for the presence of nitric oxide synthase. Light, transmission electron, and confocal laser scanning microscopy were used to study tissue sections processed for immunocytochemistry employing a monoclonal antibody ...
G P T, Martinelli, V L, Friedrich, G R, Holstein   +2 more
openaire   +2 more sources

L-Citrulline Improves Splanchnic Perfusion and Reduces Gut Injury during Exercise

Medicine & Science in Sports & Exercise, 2014
Splanchnic hypoperfusion is a physiological phenomenon during strenuous exercise. It has been associated with gastrointestinal symptoms and intestinal injury and may hamper athletic performance. We hypothesized that L-citrulline supplementation improves splanchnic perfusion and decreases intestinal injury by enhancing arginine availability.
Van Wijck, Kim, Wijnands, Karolina A. P., Meesters, Dennis M., Boonen, Bas, Van Loon, Luc J.C., Buurman, Wim A., Dejong, Cornelis H. C., Lenaerts, Kaatje, Poeze, Martijn   +8 more
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Composé moléculaire acide L-malique-L-citrulline (1/1)

Acta Crystallographica Section C Crystal Structure Communications, 1988
C 4 H 6 O 5 •C 6 H 13 N 3 O 3 cristallise dans P2 1 avec a=8,934, b=5,368 et c=14,377 A, β=91,96 o , Z=2; affinement jusqu'a R=0,039. La molecule L-citrulline est un zwitterion. Sa geometrie ne presente pas de deviations notables par rapport a la L-citrulline et a la L-citrulline dihydratee. La chaine carbonee de l'acide malique est plane et presente
P. Toffoli, N. Rodier, R. Céolin, F. Lepage, J. Astoin   +4 more
openaire   +1 more source

The crystal and molecular structure of L-citrulline hydrochloride

Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry, 1971
The crystal of L-citrulline hydrochloride C6H13N3O3. HCI,has been determined using three-dimensional photographic data. The crystals are monoclinic, space group C2, with cell dimensinos a=17.86, b=5.09, c=11.77 A and β=106.8°. Refinement was carried out with full-matrix least-squares methods, including anisotopic thermal parameters foe all non-hydrogen
P. S. Naganathan, K. Venkatesan
openaire   +1 more source

Lactobacillus murinus alleviates insulin resistance via promoting L-citrulline synthesis

Journal of Endocrinological Investigation
The role of Lactobacillus murinus as a potential probiotic is being explored. Our objectives were to explore the effects of Lactobacillus murinus on insulin resistance and the underlying mechanism.Insulin resistance animal models were applied to study the effect of L. murinus and the underlying mechanism by six weeks of treatment.
Jianglan Long, Zhe Shi, Zenghui Miao, Linjie Dong, Dan Yan   +4 more
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