Results 31 to 40 of about 2,114,876 (117)

Lack of regulation of 11 beta-hydroxysteroid dehydrogenase type 1 during short-term manipulation of GH in patients with hypopituitarism [PDF]

, 2009
Objective: Evidence from long-term clinical studies measuring urinary steroid ratios. and from in vitro studies, suggests that GH administered for longer than 2 months down-regulates 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1), thereby ...
Johannsson, Gudmundur,, Stimson, Roland H, Johannsson, Gudmundur, Andrew, Ruth, Walker, Brian R, Sigurjónsdóttir, Helga A,, Sigurjonsdottir, Helga A   +6 more
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The Pisum sativum SAD short-chain dehydrogenase/reductase: quinone reduction, tissue distribution, and heterologous expression [PDF]

, 2011
The pea (Pisum sativum) tetrameric short-chain alcohol dehydrogenase-like protein (SAD) family consists of at least three highly similar members (SAD-A, -B, and -C).
Hilja Strid, Strid, Hilja, Eriksson, Leif A.,, Nikolai Scherbak, Åke Strid, Strid, Hilja,, Anneli Ala-Häivälä, Böwer, Nathalie, Strid, Åke, Grahn, Elin M., Brosché, Mikael, Ala-Häivälä, Anneli, Gittins, John R.,, Elin Grahn, Mikael Brosché, John R. Gittins, Strid, Åke,, Grahn, Elin, Nathalie Böwer, Gittins, John R., Scherbak, Nikolai,, Eriksson, Leif A., Leif A. Eriksson, Grahn, Elin M.,, Scherbak, Nikolai, Brosché, Mikael,   +25 more
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Suppression of the Nrf2-dependent antioxidant response by glucocorticoids and 11β-HSD1-mediated glucocorticoid activation in hepatic cells [PDF]

, 2012
Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a key transcription factor regulating a plethora of detoxifying enzymes and antioxidant genes involved in drug metabolism and defence against oxidative stress.
Denise V. Kratschmar (165140), Diego Calabrese, Diego Calabrese (165146), Moulin, Pierre, Birk, Julia, Pierre Moulin, Appenzeller-Herzog, Christian, Calabrese, Diego, Christian Appenzeller-Herzog (165171), Lister Adam, Lister, Adam, Alex Odermatt (27423), Pierre Moulin (106353), Adam Lister (165158), Walsh Jo, Appenzeller-Herzog Christian, Moulin Pierre, Goldring Chris E., Chris E. Goldring (165179), Birk Julia, Jo Walsh, Jo Walsh (165152), Chris E Goldring, Kratschmar, Denise V., Denise V Kratschmar, Calabrese Diego, Goldring, Chris E., Kratschmar Denise V., Walsh, Jo, Julia Birk, Julia Birk (165165), Alex Odermatt, Odermatt Alex, Adam Lister, Odermatt, Alex, Christian Appenzeller-Herzog   +35 more
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Comparison Of The Amino Acid Sequence Of L-Mandelate Dehydrogenase From Rhodotorula Graminis With Other L-2-Hydroxyacid Dehydrogenase Enzyme And Its Primary Structure Prediction [PDF]

, 2001
A comparison of the primary structure for L-mandelate dehydrogenase (L-MDH) from Rhodotorula graminis with other proteins from the protein databank suggests that there is similarity between this protein and L-2-hydroxyacid dehydrogenase enzymes.
Nadzarah A. Wahab, Rosli Md. Illias, Graeme A. Reid, Md. Illias, Rosli, Reid, Graeme A., A. Wahab, Nadzarah   +5 more
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Chlorproguanil−Dapsone−Artesunate versus Artemether−Lumefantrine : a randomized, double-blind phase III trial in African children and adolescents with uncomplicated plasmodium falciparum malaria [PDF]

, 2009
Chlorproguanil−dapsone−artesunate (CDA) was developed as an affordable, simple, fixed-dose artemisinin-based combination therapy for use in Africa. This trial was a randomized parallel-group, double-blind, double-dummy study to compare CDA and artemether−
Peter A Winstanley, Pamba Allan, Guiguemdé, Robert, Stephan Duparc, Paula L Kirby, Esamai, Fabian, Ezedinachi, Emmanuel U, Ward, S.A., Umeh, Rich E., Borrmann Steffen, Winstanley Peter A., Kirby, Paula L., Kellam, Lynda, Premji, Z., Greenwood, Brian, Ward, Stephen A, Premji, Zul, Lynda Kellam, Ezedinachi Emmanuel U., Oguche, Stephen, Owusu-Agyei, S., Stephen Oguche, Greenwood Brian, Oguche Stephen, Owusu-Agyei Seth, Winstanley, Peter A, Oguche, S, Emmanuel U Ezedinachi, Pamba, Allan, Rich E Umeh, Greenwood, B., Umeh Rich E., Zul Premji, Kellam, L., Winstanley, P.A., Duparc, Stephan, Owusu-Agyei, Seth, Duparc Stephan, Guiguemdé Robert, Guiguemde, R., Ward, S. A., Umeh, Rich Enujioke, Allan Pamba, Ward, Steve, Fabian Esamai, Ezedinachi, Emmanuel U., Umeh, R.E., Stephen A Ward, Kellam Lynda, Premji Zul, Esamai Fabian, Duparc, S., Kirby Paula L., Sowunmi Akintunde, Kirby, Paula L, Brian Greenwood, Pamba, A., Kirby, P.L., Rénia, Laurent, Ward Stephen A., Borrmann, S., Seth Owusu-Agyei, Robert Guiguemdé, Akintunde Sowunmi, Sowunmi, Akintunde, Ezedinachi, E.U., Umeh, Rich E, Sowunmi, A., Oguche, S., Borrmann, Steffen, Esamai, F., Steffen Borrmann, Winstanley, Peter, Winstanley, Peter A.   +73 more
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Localization of TCA cycle dehydrogenases in the mitochondria

, 1967
The site of localization of TCA cycle dehydrogenases in mitochondria has been investigated by observing the dehydrogenase activities and fine structure of the fractionated samples after freezing and thawing or sonication of beef heart and rat liver ...
Oda, Takuzo, Inaba, Kozo, Wakabayashi, Akira   +2 more
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Cloning and sequence analysis of cDNAs encoding the cytosolic precursors of subunits GapA and GapB of chloroplast glyceraldehyde-3-phosphate dehydrogenase from pea and spinach [PDF]

, 1989
Chloroplast glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is composed of two different subunits, GapA and GapB. cDNA clones containing the entire coding sequences of the cytosolic precursors for GapA from pea and for GapB from pea and spinach have ...
Soll, Jürgen, Brinkmann, Henner, Cerff, Rüdiger, Salomon, Michael   +3 more
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The Plant Short-Chain Dehydrogenase (SDR) superfamily:genome-wide inventory and diversification patterns [PDF]

, 2012
Background Short-chain dehydrogenases/reductases (SDRs) form one of the largest and oldest NAD(P)(H) dependent oxidoreductase families. Despite a conserved 'Rossmann-fold' structure, members of the SDR superfamily exhibit low sequence similarities, which
Moummou, Hanane, Persson, B, van der Rest, Benoit,, Libert Brice Tonfack, Tonfack, LB, Tonfack, Libert Brice, Kallberg, Yvonne, Persson, Bengt, Bengt Persson, Kallberg, Y,, Benoît van der Rest, Moummou, Hanane,, Yvonne Kallberg, Brice Tonfack, Libert, Persson, Bengt,, Hanane Moummou, Van der Rest, Benoît, Kallberg, Yvonne,, Brice Tonfack, Libert,, van, der Rest B, Moummou, H   +20 more
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ALDH2 mediates 5-nitrofuran activity in multiple species

, 2012
Understanding how drugs work in vivo is critical for drug design and for maximizing the potential of currently available drugs. 5-nitrofurans are a class of pro-drugs widely used to treat bacterial and trypanosome infections, but despite relative ...
Spitzer, Michaela, Brear, Paul, Patton, E. Elizabeth, Johnson, Stephen L, Patton, E Elizabeth, Zeng, Zhiqiang, Patton, Elizabeth, Mitchell, Amy, Ishizaki, Hironori, Taylor, Kerrie L, Johnson, Stephen L., Taylor, Kerrie L., Smith, Terry K., Westwood, Nicholas J, Patton, E Elizabeth; id_orcid, Marie, K.L.; id_orcid, McNeil, Ewan, Temperley, Nicholas, Tyers, Mike, Melton, David W, Zhou, Linna, Temperley, Nicholas D., Temperley, Nicholas D, Gautier, Philippe, Taylor, Kerrie, Narayan, Vikram, Melton, David, Westwood, Nicholas James, Melton, David W., Smith, Terry K, Johnson, Stephen, McNeil, Ewan M, McNeil, Ewan M., Westwood, Nicholas J.   +33 more
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Hexose-6-phosphate dehydrogenase modulates the effect of inhibitors and alternative substrates of 11[beta]-hydroxysteroid dehydrogenase 1

, 2008
Intracellular glucocorticoid reactivation is catalyzed by 11[beta]-hydroxysteroid dehydrogenase 1 (11[beta]-HSD1), which functions predominantly as a reductase in cells expressing hexose-6-phosphate dehydrogenase (H6PDH).
Alex Odermatt, Nashev, L. G., Chandsawangbhuwana, C., Lyubomir G. Nashev, Balazs, Z., Michael E. Baker, Baker, M. E., Odermatt, A., Charlie Chandsawangbhuwana, Zoltán Balázs   +9 more
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