Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Robust and diverse multidimensional statistical moments in dual-band entomological lidar for improved real-time insect monitoring. [PDF]
Dreyer D +12 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Solvatochromic Study of 2‑(<i>N</i>,<i>N</i>‑dimethyl)-3-alkynyl-pyridine Fluorophores. [PDF]
Gross L +8 more
europepmc +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Separability of the Coupled-Cluster Excited State Equations: The Case of Excitonic Couplings. [PDF]
Köhn A.
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Direct demonstration of electric chirality control in a helimagnetic YMn<sub>6</sub>Sn<sub>6</sub> by spin-polarized neutron scattering. [PDF]
Masuda H +5 more
europepmc +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Compensatory Effects of Joint Bracing From a Kinetic Chain Perspective: Lower Limb Movement Coordination Analysis During Badminton Lunge Movements. [PDF]
Deng L +6 more
europepmc +1 more source

