Results 131 to 140 of about 10,531,857 (299)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Moments of the generalized hyperbolic distribution

In this paper we demonstrate a recursive method for obtaining the moments of the generalized hyperbolic distribution. The method is readily programmable for numerical evaluation of moments.
Scott, David J, Würtz, Diethelm, Tran, Thanh Tam, Dong, Christine   +3 more
core  

High moments of L-functions

, 2019
: Moments of L-functions on the critical line (Re(s) = 1/2) have been extensively studied due to numerous applications, for example, bounds for L-functions, information on zeros of L-functions, and connections to the generalized Riemann hypothesis ...
Chandee, Vorrapan
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Complete O α s 2 $$ \mathcal{O}\left({\alpha}_s^2\right) $$ corrections to the leptonic invariant mass spectrum in b → X c l ν ¯ l $$ b\to {X}_cl{\overline{\nu}}_l $$ decay

Journal of High Energy Physics
In the determination of the Cabibbo-Kobayashi-Maskawa matrix element |V cb | from inclusive semileptonic B-meson decays, moments of the leptonic invariant mass spectrum constitute valuable observables.
Mateusz Czaja, Mikołaj Misiak, Abdur Rehman   +2 more
doaj   +1 more source

On Estimation of α-Stable Distribution Using L-Moments

Fractal and Fractional
The family of stable distributions and, in particular, the α-stable distribution increases its applicability in engineering sciences. Examination of industrial data shows that originally assumed Gaussian properties are not so often observed.
Xunzhi Liao, Paweł D. Domański
doaj   +1 more source

Moments of IV and JIVE Estimators [PDF]

We develop a new method, based on the use of polar coordinates, to investigate the existence of moments for instrumental variables and related estimators in the linear regression model. For generalized IV estimators, we obtain familiar results. For JIVE,
Russell Davidson, James G. MacKinnon
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

On Some Inequalities for the Moments of Guessing Mapping

, 2001
Using some inequalities for real numbers and integrals we point out here some new inequalities for the moments of guessing mapping which generalize and improve the recent results of Arikan [2], Dragomir and van der Hoek [3]-[4] and Dragomir [10]
Pecaric, Josep, Dragomir, Sever S, Van Der Hoek, J   +2 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source