Results 91 to 100 of about 493,432 (269)

Minimal unitary representation of SU(2,2) and its deformations as massless conformal fields and their supersymmetric extensions

open access: yes, 2009
We study the minimal unitary representation (minrep) of SO(4,2) over an Hilbert space of functions of three variables, obtained by quantizing its quasiconformal action on a five dimensional space. The minrep of SO(4,2), which coincides with the minrep of
Bekaert X.   +6 more
core   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

On Pro-$p$ Cappitt Groups with finite exponent

open access: yesComptes Rendus. Mathématique
A pro-$p$ Cappitt group is a pro-$p$ group $G$ such that $\tilde{S}(G) = \overline{ \langle L \leqslant _c G \:|\, L \ntriangleleft G \rangle }$ is a proper subgroup (i.e. $\tilde{S}(G) \ne G$).
Porto, Anderson, Lima, Igor
doaj   +1 more source

On autocentral kernel of groups [PDF]

open access: yesJournal of Mahani Mathematical Research
‎Let $G$ be a group,  where $\text{Aut}(G)$ denotes the full automorphisms group of $G$  and $L(G)$ represents  the  absolute center of $G.$ An automorphism $\alpha \in \text{Aut}(G)$ is called an autocentral automorphism if $g^{-1}\alpha(g) \in L(G ...
Shafigh Bahri   +2 more
doaj   +1 more source

Treating Top Differently from Charm and Up [PDF]

open access: yes, 1995
It now appears phenomenologically that the third family may be essentially different from the first two. Particularly the high value of the top quark mass suggests a special role.
Frampton, Paul H.
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Serum Liver‐Type Fatty Acid–Binding Protein Is a Possible Prognostic Factor in Human Chronic Liver Diseases From Chronic Hepatitis to Liver Cirrhosis and Hepatocellular Carcinoma

open access: yesHepatology Communications, 2019
Liver‐type fatty acid–binding protein (L‐FABP) is a key regulator of fatty acid metabolism, but serum L‐FABP levels are not well investigated in chronic liver diseases.
Akiko Eguchi   +7 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Linear groups saturated by subgroups of finite central dimension

open access: yesДоповiдi Нацiональної академiї наук України
Let F be a field, A be a vector space over F, and G be a subgroup of GL(F, A). We say that G has a dense family of subgroups having finite central dimension, if, for every pair of subgroups H, K of G such that H ≤ K and H is not maximal in K, there ...
N.N. Semko, L.V. Skaskiv, O.A. Yarovaya
doaj   +1 more source

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